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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: LRC24_HUMAN (Q50LG9)

Summary

This is the summary of UniProt entry LRC24_HUMAN (Q50LG9).

Description: Leucine-rich repeat-containing protein 24
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 513 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 20
low_complexity n/a 1 28
low_complexity n/a 62 78
Pfam LRR_8 75 134
Pfam LRR_8 139 205
low_complexity n/a 164 177
Pfam Ig_3 259 349
disorder n/a 292 318
low_complexity n/a 311 318
disorder n/a 363 395
low_complexity n/a 363 390
low_complexity n/a 397 422
transmembrane n/a 406 426
low_complexity n/a 426 435
disorder n/a 431 433
disorder n/a 436 438
disorder n/a 440 442
disorder n/a 483 498

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q50LG9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MALRAPALLP LLLLLLPLRA AGCPAACRCY SATVECGALR LRVVPLGIPP
50
51
GTQTLFLQDN NIARLEPGAL APLAALRRLY LHNNSLRALE AGAFRAQPRL
100
101
LELALTSNRL RGLRSGAFVG LAQLRVLYLA GNQLARLLDF TFLHLPRLQE
150
151
LHLQENSIEL LEDQALAGLS SLALLDLSRN QLGTISREAL QPLASLQVLR
200
201
LTENPWRCDC ALHWLGAWIK EGGQRLLTSR DRKIMCAEPP RLALQSLLDV
250
251
SHSSLICIPP SVHVQPLELT ANLGEDLRVA CQASGYPQPL VTWRKVPQPR
300
301
EGRPRAQAQL EGGLLGLGGH SASDTGSGML FLSNITLAHA GKYECEASNA
350
351
GGAARVPFRL LVNASRQQPQ QPAQPPPPAA RPAGSEPRPE AGSMAFRALG
400
401
VATQTAIAAA IALLALTALL LVAMICRRRR RRKKARGPPG EGALFVNDYL
450
451
DGPCTFAQLE ELRDERGHEM FVINRSKPLF AEGPAEAPAD CGPEQGAGPG
500
501
LRVPPPVAYE IHC                                        
513
 

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Checksums:
CRC64:3770FA87B4B9C1DE
MD5:14cb6b01ff716da3b72d67f566caa90f

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.