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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: ZFY27_HUMAN (Q5T4F4)

Summary

This is the summary of UniProt entry ZFY27_HUMAN (Q5T4F4).

Description: Protrudin
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 411 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 22
transmembrane n/a 64 85
transmembrane n/a 91 109
transmembrane n/a 185 208
disorder n/a 234 287
low_complexity n/a 275 285
disorder n/a 289 290
disorder n/a 292 293
disorder n/a 301 302
disorder n/a 307 311
Pfam FYVE 339 411

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q5T4F4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MQTSEREGSG PELSPSVMPE APLESPPFPT KSPAFDLFNL VLSYKRLEIY
50
51
LEPLKDAGDG VRYLLRWQMP LCSLLTCLGL NVLFLTLNEG AWYSVGALMI
100
101
SVPALLGYLQ EVCRARLPDS ELMRRKYHSV RQEDLQRGRL SRPEAVAEVK
150
151
SFLIQLEAFL SRLCCTCEAA YRVLHWENPV VSSQFYGALL GTVCMLYLLP
200
201
LCWVLTLLNS TLFLGNVEFF RVVSEYRASL QQRMNPKQEE HAFESPPPPD
250
251
VGGKDGLMDS TPALTPTEDL TPGSVEEAEE AEPDEEFKDA IEETHLVVLE
300
301
DDEGAPCPAE DELALQDNGF LSKNEVLRSK VSRLTERLRK RYPTNNFGNC
350
351
TGCSATFSVL KKRRSCSNCG NSFCSRCCSF KVPKSSMGAT APEAQRETVF
400
401
VCASCNQTLS K                                          
411
 

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Checksums:
CRC64:5B86C64A398033D2
MD5:80ffb4066a779a84ad8014e2416faa22

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
FYVE 341 - 411 1X4U A 8 - 78 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.