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4  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ARTN_HUMAN (Q5T4W7)

Summary

This is the summary of UniProt entry ARTN_HUMAN (Q5T4W7).

Description: Artemin
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 220 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 2
disorder n/a 8 12
disorder n/a 14 20
low_complexity n/a 21 43
disorder n/a 38 66
low_complexity n/a 42 55
disorder n/a 68 121
low_complexity n/a 74 121
Pfam TGF_beta 121 218
low_complexity n/a 162 181
disorder n/a 165 176
disorder n/a 179 186

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q5T4W7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MELGLGGLST LSHCPWPRQQ PALWPTLAAL ALLSSVAEAS LGSAPRSPAP
50
51
REGPPPVLAS PAGHLPGGRT ARWCSGRARR PPPQPSRPAP PPPAPPSALP
100
101
RGGRAARAGG PGSRARAAGA RGCRLRSQLV PVRALGLGHR SDELVRFRFC
150
151
SGSCRRARSP HDLSLASLLG AGALRPPPGS RPVSQPCCRP TRYEAVSFMD
200
201
VNSTWRTVDR LSATACGCLG                                 
220
 

Show the unformatted sequence.

Checksums:
CRC64:C61B65EF3A51FEE4
MD5:9cc99c9e93b6b71856d015dba4d91289

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
TGF_beta 121 - 218 2ASK A 14 - 111 Jmol OpenAstexViewer
B 14 - 111 Jmol OpenAstexViewer
122 - 218 2GH0 C 122 - 218 Jmol OpenAstexViewer
D 122 - 218 Jmol OpenAstexViewer
2GYR A 4 - 100 Jmol OpenAstexViewer
B 4 - 100 Jmol OpenAstexViewer
C 4 - 100 Jmol OpenAstexViewer
D 4 - 100 Jmol OpenAstexViewer
E 4 - 100 Jmol OpenAstexViewer
F 4 - 100 Jmol OpenAstexViewer
2GYZ A 4 - 100 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.