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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: ACBD5_HUMAN (Q5T8D3)

Summary

This is the summary of UniProt entry ACBD5_HUMAN (Q5T8D3).

Description: Acyl-CoA-binding domain-containing protein 5
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 534 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam ACBP 42 121
disorder n/a 181 227
low_complexity n/a 190 214
disorder n/a 231 232
disorder n/a 245 441
low_complexity n/a 368 382
coiled_coil n/a 453 473
disorder n/a 478 496
transmembrane n/a 503 526

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q5T8D3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MFQFHAGSWE SWCCCCLIPA DRPWDRGQHW QLEMADTRSV HETRFEAAVK
50
51
VIQSLPKNGS FQPTNEMMLK FYSFYKQATE GPCKLSRPGF WDPIGRYKWD
100
101
AWSSLGDMTK EEAMIAYVEE MKKIIETMPM TEKVEELLRV IGPFYEIVED
150
151
KKSGRSSDIT SVRLEKISKC LEDLGNVLTS TPNAKTVNGK AESSDSGAES
200
201
EEEEAQEEVK GAEQSDNDKK MMKKSADHKN LEVIVTNGYD KDGFVQDIQN
250
251
DIHASSSLNG RSTEEVKPID ENLGQTGKSA VCIHQDINDD HVEDVTGIQH
300
301
LTSDSDSEVY CDSMEQFGQE ESLDSFTSNN GPFQYYLGGH SSQPMENSGF
350
351
REDIQVPPGN GNIGNMQVVA VEGKGEVKHG GEDGRNNSGA PHREKRGGET
400
401
DEFSNVRRGR GHRMQHLSEG TKGRQVGSGG DGERWGSDRG SRGSLNEQIA
450
451
LVLMRLQEDM QNVLQRLQKL ETLTALQAKS STSTLQTAPQ PTSQRPSWWP
500
501
FEMSPGVLTF AIIWPFIAQW LVYLYYQRRR RKLN                 
534
 

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Checksums:
CRC64:8BE9A09967717653
MD5:0f0b78758e4af7e618408c01fd64085f

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
ACBP 42 - 121 3FLV A 6 - 85 NGL View in InterPro
B 6 - 85 NGL View in InterPro
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The parts of the structure corresponding to the Pfam family are highlighted in yellow.

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TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.