Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MAGI3_HUMAN (Q5TCQ9)

Summary

This is the summary of UniProt entry MAGI3_HUMAN (Q5TCQ9).

Description: Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 1481 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
low_complexity n/a 1 13
low_complexity n/a 29 40
disorder n/a 44 45
disorder n/a 56 59
disorder n/a 75 76
Pfam Guanylate_kin 122 196
disorder n/a 145 146
disorder n/a 150 151
disorder n/a 182 217
disorder n/a 219 273
low_complexity n/a 237 245
disorder n/a 277 289
disorder n/a 293 299
Pfam WW 295 324
disorder n/a 323 324
disorder n/a 327 329
disorder n/a 332 333
disorder n/a 338 344
Pfam WW 341 370
disorder n/a 367 397
Pfam PDZ_6 435 492
disorder n/a 436 439
disorder n/a 444 445
disorder n/a 451 452
disorder n/a 521 526
disorder n/a 530 570
disorder n/a 575 576
disorder n/a 653 683
low_complexity n/a 679 694
disorder n/a 688 697
disorder n/a 709 714
Pfam PDZ_6 751 808
disorder n/a 821 853
Pfam PDZ 851 935
disorder n/a 864 866
disorder n/a 876 885
disorder n/a 889 891
disorder n/a 896 900
disorder n/a 933 982
disorder n/a 984 996
disorder n/a 1003 1005
disorder n/a 1019 1021
Pfam PDZ 1021 1100
disorder n/a 1064 1065
disorder n/a 1067 1073
disorder n/a 1082 1084
disorder n/a 1108 1112
disorder n/a 1116 1128
disorder n/a 1133 1136
disorder n/a 1165 1481

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q5TCQ9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSKTLKKKKH WLSKVQECAV SWAGPPGDFG AEIRGGAERG EFPYLGRLRE
50
51
EPGGGTCCVV SGKAPSPGDV LLEVNGTPVS GLTNRDTLAV IRHFREPIRL
100
101
KTVKPGKVIN KDLRHYLSLQ FQKGSIDHKL QQVIRDNLYL RTIPCTTRAP
150
151
RDGEVPGVDY NFISVEQFKA LEESGALLES GTYDGNFYGT PKPPAEPSPF
200
201
QPDPVDQVLF DNEFDAESQR KRTTSVSKME RMDSSLPEEE EDEDKEAING
250
251
SGNAENRERH SESSDWMKTV PSYNQTNSSM DFRNYMMRDE TLEPLPKNWE
300
301
MAYTDTGMIY FIDHNTKTTT WLDPRLCKKA KAPEDCEDGE LPYGWEKIED
350
351
PQYGTYYVDH LNQKTQFENP VEEAKRKKQL GQVEIGSSKP DMEKSHFTRD
400
401
PSQLKGVLVR ASLKKSTMGF GFTIIGGDRP DEFLQVKNVL KDGPAAQDGK
450
451
IAPGDVIVDI NGNCVLGHTH ADVVQMFQLV PVNQYVNLTL CRGYPLPDDS
500
501
EDPVVDIVAA TPVINGQSLT KGETCMNPQD FKPGAMVLEQ NGKSGHTLTG
550
551
DGLNGPSDAS EQRVSMASSG SSQPELVTIP LIKGPKGFGF AIADSPTGQK
600
601
VKMILDSQWC QGLQKGDIIK EIYHQNVQNL THLQVVEVLK QFPVGADVPL
650
651
LILRGGPPSP TKTAKMKTDK KENAGSLEAI NEPIPQPMPF PPSIIRSGSP
700
701
KLDPSEVYLK SKTLYEDKPP NTKDLDVFLR KQESGFGFRV LGGDGPDQSI
750
751
YIGAIIPLGA AEKDGRLRAA DELMCIDGIP VKGKSHKQVL DLMTTAARNG
800
801
HVLLTVRRKI FYGEKQPEDD SSQAFISTQN GSPRLNRAEV PARPAPQEPY
850
851
DVVLQRKENE GFGFVILTSK NKPPPGVIPH KIGRVIEGSP ADRCGKLKVG
900
901
DHISAVNGQS IVELSHDNIV QLIKDAGVTV TLTVIAEEEH HGPPSGTNSA
950
951
RQSPALQHRP MGQSQANHIP GDRSALEGEI GKDVSTSYRH SWSDHKHLAQ
1000
1001
PDTAVISVVG SRHNQNLGCY PVELERGPRG FGFSLRGGKE YNMGLFILRL
1050
1051
AEDGPAIKDG RIHVGDQIVE INGEPTQGIT HTRAIELIQA GGNKVLLLLR
1100
1101
PGTGLIPDHG DWDINNPSSS NVIYDEQSPL PPSSHFASIF EESHVPVIEE
1150
1151
SLRVQICEKA EELKDIVPEK KSTLNENQPE IKHQSLLQKN VSKRDPPSSH
1200
1201
GHSNKKNLLK VENGVTRRGR SVSPKKPASQ HSEEHLDKIP SPLKNNPKRR
1250
1251
PRDQSLSPSK GENKSCQVST RAGSGQDQCR KSRGRSASPK KQQKIEGSKA
1300
1301
PSNAEAKLLE GKSRRIAGYT GSNAEQIPDG KEKSDVIRKD AKQNQLEKSR
1350
1351
TRSPEKKIKR MVEKSLPSKM TNKTTSKEVS ENEKGKKVTT GETSSSNDKI
1400
1401
GENVQLSEKR LKQEPEEKVV SNKTEDHKGK ELEAADKNKE TGRFKPESSS
1450
1451
PVKKTLITPG PWKVPSGNKV TGTIGMAEKR Q                    
1481
 

Show the unformatted sequence.

Checksums:
CRC64:9C2B604D9B1B1B97
MD5:92134a7b702bb4ba5f02eaf1708fec1e

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.