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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: RNLS_HUMAN (Q5VYX0)

Summary

This is the summary of UniProt entry RNLS_HUMAN (Q5VYX0).

Description: Renalase {ECO:0000303|PubMed:15841207}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 342 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 16
Pfam NAD_binding_8 6 80
disorder n/a 44 47
Pfam Amino_oxidase 84 332

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q5VYX0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAQVLIVGAG MTGSLCAALL RRQTSGPLYL AVWDKAEDSG GRMTTACSPH
50
51
NPQCTADLGA QYITCTPHYA KKHQRFYDEL LAYGVLRPLS SPIEGMVMKE
100
101
GDCNFVAPQG ISSIIKHYLK ESGAEVYFRH RVTQINLRDD KWEVSKQTGS
150
151
PEQFDLIVLT MPVPEILQLQ GDITTLISEC QRQQLEAVSY SSRYALGLFY
200
201
EAGTKIDVPW AGQYITSNPC IRFVSIDNKK RNIESSEIGP SLVIHTTVPF
250
251
GVTYLEHSIE DVQELVFQQL ENILPGLPQP IATKCQKWRH SQVTNAAANC
300
301
PGQMTLHHKP FLACGGDGFT QSNFDGCITS ALCVLEALKN YI        
342
 

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Checksums:
CRC64:952827FF7926AF48
MD5:5c621a8792d355c82ea8dfbe1a958672

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Amino_oxidase 84 - 332 3QJ4 A 84 - 332 Jmol OpenAstexViewer
B 84 - 332 Jmol OpenAstexViewer
NAD_binding_8 6 - 80 3QJ4 A 6 - 80 Jmol OpenAstexViewer
B 6 - 80 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.