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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SHE_HUMAN (Q5VZ18)

Summary

This is the summary of UniProt entry SHE_HUMAN (Q5VZ18).

Description: SH2 domain-containing adapter protein E
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 495 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 32 33
disorder n/a 49 149
low_complexity n/a 70 80
disorder n/a 151 189
low_complexity n/a 161 180
disorder n/a 202 328
disorder n/a 348 391
Pfam SH2 395 471
disorder n/a 395 396
disorder n/a 415 417

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q5VZ18. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MQWSPTPGAS ACLGWASSLA CSTAPTLLGR AGRGPLMAAK WFKEFPLNLK
50
51
TVSERAKPGG GGGKLRKNSE AGGAGPGPGK GRKNSAAELG SGRAGVGPKD
100
101
SRLSRDSLQG LIQAAAGKGR KNSRATEEEP HRGATKSSGC STYINRLIKV
150
151
DTQEKNGKSN YPSSSSSSSS SSSSASSSPS SLGPELDKGK IIKQQETVII
200
201
LEDYADPYDA KRTKGQRDAE RVGENDGYME PYDAQQMITE IRRRGSKDPL
250
251
VKALQLLDSP CEPADGGLKS ETLAKRRSSK DLLGKPPQLY DTPYEPAEGG
300
301
PRAEGKARPP DSRLPENDER PAAEYEQPWE WKKEQIVRAL SVQFEGAERP
350
351
SFREETVRQH HRQKSWTQKI LKPALSDHSE GEKVDPGLPL EKQPWYHGAI
400
401
SRAEAESRLQ PCKEAGYLVR NSESGNSRYS IALKTSQGCV HIIVAQTKDN
450
451
KYTLNQTSAV FDSIPEVVHY YSNEKLPFKG AEHMTLLYPV HSKLH     
495
 

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Checksums:
CRC64:7E1E3D9645B00536
MD5:e09f05b6d54e9dc9294b4782b321ffff

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.