Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SPT6H_MOUSE (Q62383)

Summary

This is the summary of UniProt entry SPT6H_MOUSE (Q62383).

Description: Transcription elongation factor SPT6
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 1726 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
disorder n/a 1 108
low_complexity n/a 2 23
coiled_coil n/a 28 51
low_complexity n/a 32 50
Pfam SPT6_acidic 35 127
low_complexity n/a 60 81
low_complexity n/a 93 108
disorder n/a 119 189
low_complexity n/a 122 143
low_complexity n/a 146 164
low_complexity n/a 170 189
low_complexity n/a 192 203
disorder n/a 195 201
disorder n/a 204 205
disorder n/a 211 214
disorder n/a 216 217
low_complexity n/a 220 250
disorder n/a 227 257
low_complexity n/a 252 267
disorder n/a 274 289
Pfam HTH_44 305 433
low_complexity n/a 307 318
disorder n/a 342 347
disorder n/a 349 353
disorder n/a 436 442
disorder n/a 486 520
low_complexity n/a 494 509
disorder n/a 547 562
disorder n/a 618 619
disorder n/a 764 770
Pfam YqgF 775 931
disorder n/a 820 822
disorder n/a 825 827
Pfam HHH_7 935 1038
Pfam HHH_9 1051 1138
disorder n/a 1085 1090
disorder n/a 1148 1149
disorder n/a 1180 1184
Pfam S1 1224 1282
low_complexity n/a 1248 1259
Pfam SH2_2 1300 1514
disorder n/a 1311 1319
disorder n/a 1322 1323
disorder n/a 1351 1355
low_complexity n/a 1441 1454
disorder n/a 1519 1540
disorder n/a 1565 1591
low_complexity n/a 1586 1599
disorder n/a 1595 1726
low_complexity n/a 1639 1664

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q62383. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSDFVESEAE ESEEEYNHEG EVVPRVTKKF VEEEDDDEEE EEENLDDQDE
50
51
RGNLKDFIND DDDEEEGEED EGSDSGDSED DVGHKKRKRP SFDDRLEDDD
100
101
FDLIEENLGV KVKRGQKYRR VKKMSDDDED DEEEYGKEEH EKEAIAGEIF
150
151
QDEEGEEGQE AVEAPMAPPD EEEEDDEESD IDDFIVDDDG QPLKKPKWRK
200
201
KLPGYTDAAL QEAQEIFGVD FDYDEFEKYN EYDEELEEDY EYEDDETEGE
250
251
IRVRPKKTTK KRVSRRSIFE MYEPSELESS HLTDQDNEIR ATDLPERFQL
300
301
RSIPVKAAED DELEEEADWI YRNAFATPTI SLQDSCDYLD RGQPTSSFSR
350
351
KGPSTVQKIK EALGFMRNQH FEVPFIAFYR KEYVEPELHI NDLWRVWQWD
400
401
EKWTQLRIRK ENLTRLFEKM QAYQYEQISA DPDKPLADGI RALDTTDMER
450
451
LKDVQSMDEL KDVYNHFLLY YGRDIPKMQN AAKASRKKLK RIKEDGDEEG
500
501
EGEEAEDEEQ RGPELKQASR RDMYTICQSA GLDGLAKKFG LTPEQFGENL
550
551
RDSYQRHETE QFPAEPLELA KDYVCSQFPT PEAVLEGARY MVALQIAREP
600
601
LVRQVLRQTF QERAKLNITP TKKGRKDVDE AHYAYSFKYL KNKPVKELRD
650
651
DQFLKIGLAE DEGLLTIDIS IDMKGVEGYG NDQTYFEEIK QFYYRDEFSH
700
701
QVQEWNRQRT MAIERALQQF LYVQMAKELK NKLLAEARES VVKACSRKLY
750
751
NWLRVAPYRP DQQVEEDDDF MDENQGKGIR VLGIAFSSAR DHPVFCALVN
800
801
GEGEVTDFLR LPHFTKRRTA WREEEREKKA QDIETLKKFL VNKKPHVVTI
850
851
AGENRDAQML TEDVKRIVHE LDQGQQLSSI GVELVDNELA ILYMNSKKSE
900
901
AEFRDYPPVL RQAVSLARRI QDPLIEFAQV CSSDEDILCL KFHPLQEHVV
950
951
KEELLNALYC EFINRVNEVG VDVNRAIAHP YSQALIQYVC GLGPRKGTHL
1000
1001
LKILKQNNTR LESRTQLVTM CHMGPKVFMN CAGFLKIDTA SLGDSTDSYI
1050
1051
EVLDGSRVHP ETYEWARKMA VDALEYDESA EDANPAGALE EILENPERLK
1100
1101
DLDLDAFAEE LERQGYGDKH ITLYDIRAEL SCRYKDLRTA YRSPNTEEIF
1150
1151
NMLTKETPET FYIGKLIICN VTGIAHRRPQ GESYDQAIRN DETGLWQCPF
1200
1201
CQQDNFPELS EVWNHFDSGS CPGQAIGVKT RLDNGVTGFI PTKFLSDKVV
1250
1251
KRPEERVKVG MTVHCRIMKI DIEKFSADLT CRTSDLMDRN NEWKLPKDTY
1300
1301
YDFDAEAADH KQEEDMKRKQ QRTTYIKRVI AHPSFHNINF KQAEKMMETM
1350
1351
DQGDVIIRPS SKGENHLTVT WKVSAGIYQH VDVREEGKEN AFSLGATLWI
1400
1401
NSEEFEDLDE IVARYVQPMA SFARDLLNHK YYQDCSGGDR KKLEELLIKT
1450
1451
KKEKPTFIPY FICACKELPG KFLLGYQPRG KPRIEYVTVT PEGFRYRGQI
1500
1501
FPTVNGLFRW FKDHYQDPVP GITPSSSNRT RTPASINATP ANINLADLTR
1550
1551
AVNALPQNMT SQMFSAIAAV TGQGQNPNAT PAQWASSQYG YGGSGGGSSA
1600
1601
YHVFPTPAQQ PVATPLMTPS YSYTTPSQPI TTPQYHQLQA STTPQSTQAQ
1650
1651
PQPSSSSRQR QQQPKSNSHA AIDWGKMAEQ WLQEKEAERR KQKQRLTPRP
1700
1701
SPSPMIESTP MSIAGDATPL LDEMDR                          
1726
 

Show the unformatted sequence.

Checksums:
CRC64:98BD891493372166
MD5:6e0168daa08d6c4a0fb4e5eba365c23b

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;