Summary
This is the summary of UniProt entry DEN2C_HUMAN (Q68D51).
| Description: | DENN domain-containing protein 2C |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
| Length: | 928 amino acids |
| Reference Proteome: |
|
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
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| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 5 | 6 |
| disorder | n/a | 27 | 30 |
| disorder | n/a | 63 | 71 |
| disorder | n/a | 74 | 105 |
| disorder | n/a | 129 | 131 |
| disorder | n/a | 200 | 208 |
| disorder | n/a | 244 | 265 |
| disorder | n/a | 274 | 276 |
| disorder | n/a | 279 | 280 |
| disorder | n/a | 283 | 297 |
| disorder | n/a | 325 | 327 |
| disorder | n/a | 344 | 347 |
| disorder | n/a | 350 | 362 |
| disorder | n/a | 364 | 366 |
| disorder | n/a | 370 | 374 |
| disorder | n/a | 428 | 471 |
| disorder | n/a | 476 | 478 |
| low_complexity | n/a | 484 | 497 |
| Pfam | uDENN | 510 | 578 |
| disorder | n/a | 520 | 525 |
| disorder | n/a | 527 | 528 |
| Pfam | DENN | 586 | 770 |
| Pfam | dDENN | 847 | 895 |
Show or hide domain scores.
Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q68D51. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MDVGFSRTTV QTLSRSHCKN IKQKISQWEG RANGISNPEK WCPKDFGVRY
50 51
NCHQEIRLKK NPIAERKSKN LDVTSRENVG LDINENTKSH DQSENENKKH
100 101
EYDDTHFFKN ESESNWVCSR VKEIESCKED VLDPETSLPP GNFYTSQILW
150 151
KKIEALPPDK LLNLALEHCD SSEKELNFRV LDSSYGITKS LENIYSEPEG
200 201
QECGPSINPL PKPRRTFRYL SESGVTPYKE RNCDKKYCEN NSCAQSSLAS
250 251
SQEPEPKKYG GKIRGRSKRK SFEFEDIQHF RNRNSQTIRE ELGRNSGSAL
300 301
YYTQSEDNIY EDIIYPTKEN PYEDIPVQPL PMWRSPSAWK LPPAKSAFKA
350 351
PKLPPKPQFL HRKTMEVKNS QAYLRSKLTK DTTLPVTLTE WKLFRAGEVA
400 401
NTKRKNLPRL VLKIDDIFES KRGKKKVKLH SYTGKELPPT KGETSGNESD
450 451
AEYLPKNRHK RLAQLQPSSK RNPHYQTLER DLIELQEQQL FELFVVVSLQ
500 501
KKPSGISYIP QVIQQFPGKD DHGYKQSKDM EERLKVIPKF CFPDSKDWMP
550 551
TSELKSETFS FVLTGEDGSR WFGYCKKLLP VGKGKRLPEV YCMVSRLGCF
600 601
NLFSKILDEV EKRREMSPAL VYPFMRSVME APFPAPGRTI TVKSYLPGAG
650 651
DESIELCRPL DSRLEHVDFK CLFKCLSVCH LIRVCASLLL ERRVIFVANS
700 701
LSTLSKCGHA VVATLYPFTW QHTYIPVLPA SMIDIVCSPT PFLIGILSCS
750 751
LPQLQDLPIE EVLIVDLCAD KFLQEVSDED EILPPKLQAA LMQILEERNE
800 801
ILTQEQNFSQ DVTLNSLVSE AFVRFFVELV GHYSLNMTVT ERGERVFQRE
850 851
PFRKSHTSRS VRHFLDLFME TQMFAGFIQD RELRKSGVKG LFEIRAIQYL
900 901
ETIPESEPSG MNRILRSLGS KMKFLQKK
928
Show the unformatted sequence. |
| Checksums: |
CRC64:2B450938D2199731
MD5:83c7b364faeaf7743bc02b5f3b562177
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
AlphaFold Structure Prediction
The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.
Model confidence scale
| Very High (pLDDT > 90) | |
| Confident (90 > pLDDT > 70) | |
| Low (70 > pLDDT > 50) | |
| Very Low (pLDDT < 50) |
