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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CDCA2_HUMAN (Q69YH5)

Summary

This is the summary of UniProt entry CDCA2_HUMAN (Q69YH5).

Description: Cell division cycle-associated protein 2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 1023 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 21
disorder n/a 24 29
disorder n/a 31 53
disorder n/a 68 71
disorder n/a 84 85
disorder n/a 88 96
disorder n/a 98 110
disorder n/a 115 136
disorder n/a 166 167
disorder n/a 175 176
disorder n/a 178 181
disorder n/a 207 212
low_complexity n/a 257 271
disorder n/a 291 303
disorder n/a 306 315
disorder n/a 351 352
disorder n/a 354 355
disorder n/a 362 367
low_complexity n/a 365 380
disorder n/a 371 372
disorder n/a 378 383
Pfam PP1_bind 389 449
disorder n/a 400 412
disorder n/a 414 417
disorder n/a 433 455
disorder n/a 476 510
disorder n/a 532 566
low_complexity n/a 563 570
disorder n/a 569 581
disorder n/a 586 614
disorder n/a 617 648
disorder n/a 667 721
low_complexity n/a 678 690
disorder n/a 723 738
disorder n/a 774 778
disorder n/a 803 823
disorder n/a 838 861
low_complexity n/a 852 862
disorder n/a 875 878
disorder n/a 880 896
coiled_coil n/a 883 903
disorder n/a 911 912
disorder n/a 919 921
disorder n/a 923 926
disorder n/a 935 981
disorder n/a 990 1023

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q69YH5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDANSKDKPP ETKESAMNNA GNASFILGTG KIVTPQKHAE LPPNPCTPDT
50
51
FKSPLNFSTV TVEQLGITPE SFVRNSAGKS SSYLKKCRRR SAVGARGSPE
100
101
TNHLIRFIAR QQNIKNARKS PLAQDSPSQG SPALYRNVNT LRERISAFQS
150
151
AFHSIKENEK MTGCLEFSEA GKESEMTDLT RKEGLSACQQ SGFPAVLSSK
200
201
RRRISYQRDS DENLTDAEGK VIGLQIFNID TDRACAVETS VDLSEISSKL
250
251
GSTQSGFLVE ESLPLSELTE TSNALKVADC VVGKGSSDAV SPDTFTAEVS
300
301
SDAVPDVRSP ATPACRRDLP TPKTFVLRSV LKKPSVKMCL ESLQEHCNNL
350
351
YDDDGTHPSL ISNLPNCCKE KEAEDEENFE APAFLNMRKR KRVTFGEDLS
400
401
PEVFDESLPA NTPLRKGGTP VCKKDFSGLS SLLLEQSPVP EPLPQPDFDD
450
451
KGENLENIEP LQVSFAVLSS PNKSSISETL SGTDTFSSSN NHEKISSPKV
500
501
GRITRTSNRR NQLVSVVEES VCNLLNTEVQ PCKEKKINRR KSQETKCTKR
550
551
ALPKKSQVLK SCRKKKGKGK KSVQKSLYGE RDIASKKPLL SPIPELPEVP
600
601
EMTPSIPSIR RLGSGYFSSN GKLEEVKTPK NPVKRKDLLR HDPDLHMHQG
650
651
YDKYDVSEFC SYIKSSSSLG NATSDEDPNT NIMNINENKN IPKAKNKSES
700
701
ENEPKAGTDS PVSCASVTEE RVASDSPKPA LTLQQGQEFS AGGQNAENLC
750
751
QFFKISPDLN IKCERKDDFL GAAEGKLQCN RLMPNSQKDC HCLGDVLIEN
800
801
TKESKSQSED LGRKPMESSS VVSCRDRKDR RRSMCYSDGR SLHLEKNGNH
850
851
TPSSSVGSSV EISLENSELF KDLSDAIEQT FQRRNSETKV RRSTRLQKDL
900
901
ENEGLVWISL PLPSTSQKAK RRTICTFDSS GFESMSPIKE TVSSRQKPQM
950
951
APPVSDPENS QGPAAGSSDE PGKRRKSFCI STLANTKATS QFKGYRRRSS
1000
1001
LNGKGESSLT ALERIEHNGE RKQ                             
1023
 

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Checksums:
CRC64:2A073D6DD928B1E5
MD5:0f0f6ff04d676aeaa822ad16a951ac07

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
PP1_bind 390 - 422 5INB B 390 - 422 Jmol OpenAstexViewer
391 - 423 5IOH B 391 - 423 Jmol OpenAstexViewer
392 - 421 5IOH D 392 - 421 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.