Summary
This is the summary of UniProt entry CDCA2_HUMAN (Q69YH5).
Description: | Cell division cycle-associated protein 2 |
Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
Length: | 1023 amino acids |
Reference Proteome: |
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Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
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Source | Domain | Start | End |
---|---|---|---|
disorder | n/a | 1 | 21 |
disorder | n/a | 24 | 29 |
disorder | n/a | 31 | 53 |
disorder | n/a | 68 | 71 |
disorder | n/a | 84 | 85 |
disorder | n/a | 88 | 96 |
disorder | n/a | 98 | 110 |
disorder | n/a | 115 | 136 |
disorder | n/a | 166 | 167 |
disorder | n/a | 175 | 176 |
disorder | n/a | 178 | 181 |
disorder | n/a | 207 | 212 |
low_complexity | n/a | 257 | 271 |
disorder | n/a | 291 | 303 |
disorder | n/a | 306 | 315 |
disorder | n/a | 351 | 352 |
disorder | n/a | 354 | 355 |
disorder | n/a | 362 | 367 |
low_complexity | n/a | 365 | 380 |
disorder | n/a | 371 | 372 |
disorder | n/a | 378 | 383 |
Pfam | PP1_bind | 389 | 449 |
disorder | n/a | 400 | 412 |
disorder | n/a | 414 | 417 |
disorder | n/a | 433 | 455 |
disorder | n/a | 476 | 510 |
disorder | n/a | 532 | 566 |
low_complexity | n/a | 563 | 570 |
disorder | n/a | 569 | 581 |
disorder | n/a | 586 | 614 |
disorder | n/a | 617 | 648 |
disorder | n/a | 667 | 721 |
low_complexity | n/a | 678 | 690 |
disorder | n/a | 723 | 738 |
disorder | n/a | 774 | 778 |
disorder | n/a | 803 | 823 |
disorder | n/a | 838 | 861 |
low_complexity | n/a | 852 | 862 |
disorder | n/a | 875 | 878 |
disorder | n/a | 880 | 896 |
coiled_coil | n/a | 883 | 903 |
disorder | n/a | 911 | 912 |
disorder | n/a | 919 | 921 |
disorder | n/a | 923 | 926 |
disorder | n/a | 935 | 981 |
disorder | n/a | 990 | 1023 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q69YH5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
Sequence: | 1
MDANSKDKPP ETKESAMNNA GNASFILGTG KIVTPQKHAE LPPNPCTPDT
50 51
FKSPLNFSTV TVEQLGITPE SFVRNSAGKS SSYLKKCRRR SAVGARGSPE
100 101
TNHLIRFIAR QQNIKNARKS PLAQDSPSQG SPALYRNVNT LRERISAFQS
150 151
AFHSIKENEK MTGCLEFSEA GKESEMTDLT RKEGLSACQQ SGFPAVLSSK
200 201
RRRISYQRDS DENLTDAEGK VIGLQIFNID TDRACAVETS VDLSEISSKL
250 251
GSTQSGFLVE ESLPLSELTE TSNALKVADC VVGKGSSDAV SPDTFTAEVS
300 301
SDAVPDVRSP ATPACRRDLP TPKTFVLRSV LKKPSVKMCL ESLQEHCNNL
350 351
YDDDGTHPSL ISNLPNCCKE KEAEDEENFE APAFLNMRKR KRVTFGEDLS
400 401
PEVFDESLPA NTPLRKGGTP VCKKDFSGLS SLLLEQSPVP EPLPQPDFDD
450 451
KGENLENIEP LQVSFAVLSS PNKSSISETL SGTDTFSSSN NHEKISSPKV
500 501
GRITRTSNRR NQLVSVVEES VCNLLNTEVQ PCKEKKINRR KSQETKCTKR
550 551
ALPKKSQVLK SCRKKKGKGK KSVQKSLYGE RDIASKKPLL SPIPELPEVP
600 601
EMTPSIPSIR RLGSGYFSSN GKLEEVKTPK NPVKRKDLLR HDPDLHMHQG
650 651
YDKYDVSEFC SYIKSSSSLG NATSDEDPNT NIMNINENKN IPKAKNKSES
700 701
ENEPKAGTDS PVSCASVTEE RVASDSPKPA LTLQQGQEFS AGGQNAENLC
750 751
QFFKISPDLN IKCERKDDFL GAAEGKLQCN RLMPNSQKDC HCLGDVLIEN
800 801
TKESKSQSED LGRKPMESSS VVSCRDRKDR RRSMCYSDGR SLHLEKNGNH
850 851
TPSSSVGSSV EISLENSELF KDLSDAIEQT FQRRNSETKV RRSTRLQKDL
900 901
ENEGLVWISL PLPSTSQKAK RRTICTFDSS GFESMSPIKE TVSSRQKPQM
950 951
APPVSDPENS QGPAAGSSDE PGKRRKSFCI STLANTKATS QFKGYRRRSS
1000 1001
LNGKGESSLT ALERIEHNGE RKQ
1023
Show the unformatted sequence. |
Checksums: |
CRC64:2A073D6DD928B1E5
MD5:0f0f6ff04d676aeaa822ad16a951ac07
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
---|---|---|---|---|---|
PP1_bind | 390 - 422 | 5INB | B | 390 - 422 | Jmol OpenAstexViewer |
391 - 423 | 5IOH | B | 391 - 423 | Jmol OpenAstexViewer | |
392 - 421 | 5IOH | D | 392 - 421 | Jmol OpenAstexViewer |
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.