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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DPOLB_DANRE (Q6DRD3)

Summary

This is the summary of UniProt entry DPOLB_DANRE (Q6DRD3).

Description: DNA polymerase beta EC=2.7.7.7 EC=4.2.99.-
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 336 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 6
Pfam HHH_8 11 77
coiled_coil n/a 21 41
Pfam DNA_pol_lambd_f 97 146
Pfam DNA_pol_B_palm 148 263
disorder n/a 238 240
low_complexity n/a 242 250
Pfam DNA_pol_B_thumb 269 335

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q6DRD3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
SKRKAPQESL NEGITDFLVE LANYERNVNR AIHKYNAYRK AASVIAKYPQ
50
51
KIKSGTEAKK LDGVGAKIAE KIDEFLTTGK LRKLEKIRND DTSSSINFLT
100
101
RVTGIGPAAA RKFFDEGVRN LEDLKKIEHK LNHHQQIGLK YFEEFEKRIP
150
151
RSEMQKMEAL ILKELDIVDP EYIGTICGSY RRGAESSGDI DILLTHPDFT
200
201
SQSEKQPKLL HAVVDHLESI GFITDTLSKG DTKFMGVCQL QKEKEEEEEE
250
251
SLHRRIDIRL IPKDQYYCGV LYFTGSDIFN KNMRTHALEK GFTLNEYTIR
300
301
PLGVTGVAGE PLLVDSEKDI FEYIQWKYRE PKDRSE               
336
 

Show the unformatted sequence.

Checksums:
CRC64:FDF6EA3088354973
MD5:9ba93cf51a5d2cf14b0e0dca74c04d2e

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;