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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: KD5BB_DANRE (Q6IQX0)

Summary

This is the summary of UniProt entry KD5BB_DANRE (Q6IQX0).

Description: Lysine-specific demethylase 5B-B
Source organism: Danio rerio (Zebrafish) (Brachydanio rerio) (NCBI taxonomy ID 7955)
Length: 1503 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 13
Pfam JmjN 16 49
Pfam ARID 82 166
disorder n/a 187 192
disorder n/a 195 247
disorder n/a 259 286
low_complexity n/a 269 289
Pfam PHD 297 345
Pfam JmjC 472 588
low_complexity n/a 646 657
Pfam zf-C5HC2 678 730
Pfam PLU-1 743 1079
disorder n/a 810 819
coiled_coil n/a 848 868
low_complexity n/a 892 903
coiled_coil n/a 945 972
disorder n/a 968 970
low_complexity n/a 1092 1100
Pfam PHD 1170 1216
disorder n/a 1269 1284
low_complexity n/a 1330 1343
disorder n/a 1352 1450
low_complexity n/a 1426 1443

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q6IQX0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTQQGPAEFT PPPECPVFEP SWEEFKDPFA FINKIRPIAE KTGICKVRPP
50
51
PDWQPPFACD VDRLHFTPRI QRLNELEAQT RVKLNFLDQI AKFWDLQGCT
100
101
LKIPHVERKI LDLYQLNKLV ADEGGFDLVC RERRWTKIAM TMGFAPGKAV
150
151
GSHLRAHYER ILYPYNLFQS GTNLLCLQKP GDEVNDIDKE YKPHDLLQRQ
200
201
NVPLQPSNTS APARRAKRMK TESGCIKSEE GEGVENKPNL RRRMGSFVVK
250
251
TEPKKEIPIQ VKEEPVEIKE LNPEPEKSKP KKKNIPPPPV SMVDLYVCLV
300
301
CGKGNDEDRL LLCDGCDDSY HTFCLIPPLT DVPKGDWRCP KCLTQECCKP
350
351
QEAFGFEQAH RDYTLKAFGE MADSFKSDYF NMPVHMVPTE LVEKEFWRLV
400
401
GTIQEDVTVE YGADIASKEF GSGFPIKGGR FKIAPHDEKY LQCGWNLNNM
450
451
AMMTPSVLTH VTADICGMTL PWLYVGMCFS SFCWHIEDHW SYSINYLHWG
500
501
EPKTWYGAPG FAAEQLEAVM KKLAPELFDS QPDLLHQLVT IMNPNTLMAH
550
551
GVPIYRTNQC AGEFVITFPR SYHSGFNQGF NFAEAVNFCT VDWMPLGRQC
600
601
VDHYRQLHRY CVFSHDEMVC NMAMKADCLD VVLASAVQKD MQLMIKEERE
650
651
LREKVRKMGV AQCELFQYDL LADDERQCVK CRTTCYLSAL TCPCRPGVQV
700
701
CLYHTHDLCS CPISNYTLNY RFTLDDLYPM MNAVRQRAEY YDDWASRVTE
750
751
VMEAKLDKKR NVTVFRTLLE ESNEQSFPEN DLLRQLRLVT QDAEKCSSVA
800
801
QQLLNGKRQT RYRTGKAKSP NQLTVEEMRS FVRQLYNLPC SLTQAPLLKE
850
851
LLNSIEDFQQ HSEKLLSDEV SADAVSEIES LLEEGSQFDV FLPELPLLRE
900
901
RLEQARWLTG VHQAEDPVAN PCGLSLESMR RLIDRGVGLT PHPSIERMMA
950
951
RLQELLTVSE ELEENAQALL KARPPESLET LCSMLTQVEG VPAYLPNCLL
1000
1001
LQDTVNRAKE WLQEAESLQV GGQVPVFSSL SDMVLRAHSI PVRLEPLDQL
1050
1051
EVQVSEVQSW KETAAKTFLI KSSPFTLLEV LCPRWEMGSS LKKKKMRKMK
1100
1101
GDCVSSGKKK FVKLDSMSDV ERALSDSKDS ASAMFTLAEV RLKELESLCS
1150
1151
LRASNESKLL PTADCASLKV CVCQKPAMGA MLQCELCRDA FHSVCVRGPS
1200
1201
DPLDPEAWLC PLCLRSTKPP LDKIRSLLSS LQRIRVRLPE GDALRYMIER
1250
1251
SVSWQRRVRE VIDSYGLSST SQDGRGASPS QNLYRSTGHS RKLQLCGSPS
1300
1301
RCQDWAVSGQ EQTVFYTEQR CIPLQGLSPE LEELMVEGLV LQVSLPETQQ
1350
1351
LYRLLLSGPP TTNTSHAEHK SYLTPPQTET DAITSAEKKA KRRMNRDEVD
1400
1401
IRERGTKLKS KKQRMMGVEK RRERKAASVS ASDMSQSEDS EEDMTLCPAE
1450
1451
SCLQPEGEEV DWVQCDCCNR WFHMICVGVS AELAAEEDYM CVSCSTSHMD
1500
1501
RRK                                                   
1503
 

Show the unformatted sequence.

Checksums:
CRC64:B6CE3A9BA82F506F
MD5:a7cd6e22482ac1edea93a8a8709e1c6c

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;