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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TS101_RAT (Q6IRE4)

Summary

This is the summary of UniProt entry TS101_RAT (Q6IRE4).

Description: Tumor susceptibility gene 101 protein
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 391 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam UEV 21 141
low_complexity n/a 173 199
disorder n/a 176 177
disorder n/a 182 229
coiled_coil n/a 240 312
disorder n/a 242 247
disorder n/a 249 273
disorder n/a 275 277
disorder n/a 300 307
disorder n/a 313 314
Pfam Vps23_core 317 380

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q6IRE4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAVSESQLKK MMSKYKYRDL TVRQTVNVIA MYKDLKPVLD SYVFNDGSSR
50
51
ELVNLTGTIP VRYRGNIYNI PICLWLLDTY PYNPPICFVK PTSSMTIKTG
100
101
KHVDANGKIY LPYLHDWKHP RSELLELIQI MIVIFGEEPP VFSRPTVSAS
150
151
YPPYTAAGPP NTSYLPSMPS GISAYPSGYP PNPSGYPGCP YPPAGPYPAT
200
201
TSSQYPSQPP VTTAGPSRDG TISEDTIRAS LISAVSDKLR WRMKEEMDGA
250
251
QAELNALKRT EEDLKKGHQK LEEMVTRLDQ EVAEVDKNIE LLKKKDEELS
300
301
SALEKMENQS ENNDIDEVII PTAPLYKQIL NLYAEENAIE DTIFYLGEAL
350
351
RRGVIDLDVF LKHVRLLSRK QFQLRALMQK ARKTAGLSDL Y         
391
 

Show the unformatted sequence.

Checksums:
CRC64:9403128B347CCF73
MD5:66071bd5046a38d9011cf8549fb10608

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;