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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ZSC25_HUMAN (Q6NSZ9)

Summary

This is the summary of UniProt entry ZSC25_HUMAN (Q6NSZ9).

Description: Zinc finger and SCAN domain-containing protein 25
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 544 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 9
Pfam SCAN 38 127
disorder n/a 111 117
disorder n/a 126 132
disorder n/a 135 136
disorder n/a 139 147
disorder n/a 155 226
disorder n/a 230 243
disorder n/a 250 252
disorder n/a 258 259
disorder n/a 263 289
disorder n/a 302 336
low_complexity n/a 314 327
Pfam zf-C2H2 348 370
disorder n/a 361 365
Pfam zf-C2H2 375 397
Pfam zf-C2H2 403 425
disorder n/a 419 421
disorder n/a 423 424
Pfam zf-C2H2 431 453
disorder n/a 447 449
Pfam zf-C2H2 459 480
disorder n/a 474 476
Pfam zf-C2H2 486 508
disorder n/a 502 504
disorder n/a 506 507
Pfam zf-C2H2 514 537
disorder n/a 527 544

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q6NSZ9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLKEHPEMAE APQQQLGIPV VKLEKELPWG RGREDPSPET FRLRFRQFRY
50
51
QEAAGPQEAL RELQELCRRW LRPELHTKEQ ILELLVLEQF LTILPREFYA
100
101
WIREHGPESG KALAAMVEDL TERALEAKAV PCHRQGEQEE TALCRGAWEP
150
151
GIQLGPVEVK PEWGMPPGEG VQGPDPGTEE QLSQDPGDET RAFQEQALPV
200
201
LQAGPGLPAV NPRDQEMAAG FFTAGSQGLG PFKDMALAFP EEEWRHVTPA
250
251
QIDCFGEYVE PQDCRVSPGG GSKEKEAKPP QEDLKGALVA LTSERFGEAS
300
301
LQGPGLGRVC EQEPGGPAGS APGLPPPQHG AIPLPDEVKT HSSFWKPFQC
350
351
PECGKGFSRS SNLVRHQRTH EEKSYGCVEC GKGFTLREYL MKHQRTHLGK
400
401
RPYVCSECWK TFSQRHHLEV HQRSHTGEKP YKCGDCWKSF SRRQHLQVHR
450
451
RTHTGEKPYT CECGKSFSRN ANLAVHRRAH TGEKPYGCQV CGKRFSKGER
500
501
LVRHQRIHTG EKPYHCPACG RSFNQRSILN RHQKTQHRQE PLVQ      
544
 

Show the unformatted sequence.

Checksums:
CRC64:E63AA7ACDA7E7E8B
MD5:3260577fb5773617f3d126c4abf4b1ff

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;