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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CNKR3_HUMAN (Q6P9H4)

Summary

This is the summary of UniProt entry CNKR3_HUMAN (Q6P9H4).

Description: Connector enhancer of kinase suppressor of ras 3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 555 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam SAM_1 5 69
Pfam CRIC_ras_sig 80 172
disorder n/a 106 112
Pfam PDZ 211 290
disorder n/a 238 240
disorder n/a 242 255
disorder n/a 300 302
disorder n/a 308 334
low_complexity n/a 316 329
Pfam CNK2_3_dom 332 545
disorder n/a 338 340
disorder n/a 346 353
low_complexity n/a 347 356
disorder n/a 355 360
disorder n/a 362 403
disorder n/a 405 435
disorder n/a 437 452
disorder n/a 458 461
low_complexity n/a 468 481
disorder n/a 476 488
disorder n/a 516 534
low_complexity n/a 521 539

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q6P9H4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEPVTKWSPK QVVDWTRGLD DCLQQYVHKF EREKINGEQL LQISHQDLEE
50
51
LGVTRIGHQE LVLEAVDLLC ALNYGLETDN MKNLVLKLRA SSHNLQNYIS
100
101
SRRKSPAYDG NTSRKAPNEF LTSVVELIGA AKALLAWLDR APFTGITDFS
150
151
VTKNKIIQLC LDLTTTVQKD CFVAEMEDKV LTVVKVLNGI CDKTIRSTTD
200
201
PVMSQCACLE EVHLPNIKPG EGLGMYIKST YDGLHVITGT TENSPADRSQ
250
251
KIHAGDEVIQ VNQQTVVGWQ LKNLVKKLRE NPTGVVLLLK KRPTGSFNFT
300
301
PAPLKNLRWK PPLVQTSPPP ATTQSPESTM DTSLKKEKSA ILDLYIPPPP
350
351
AVPYSPRDEN GSFVYGGSSK CKQPLPGPKG SESPNSFLDQ ESRRRRFTIA
400
401
DSDQLPGYSV ETNILPTKMR EKTPSYGKPR PLSMPADGNW MGIVDPFARP
450
451
RGHGRKGEDA LCRYFSNERI PPIIEESSSP PYRFSRPTTE RHLVRGADYI
500
501
RGSRCYINSD LHSSATIPFQ EEGTKKKSGS SATKSSSTEP SLLVSWFTRL
550
551
KLLTH                                                 
555
 

Show the unformatted sequence.

Checksums:
CRC64:456E284566D5EFC8
MD5:28577e3c43ef1ebecc5525881795fafc

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;