Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: I20RB_HUMAN (Q6UXL0)

Summary

This is the summary of UniProt entry I20RB_HUMAN (Q6UXL0).

Description: Interleukin-20 receptor subunit beta
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 311 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam Tissue_fac 15 124
Pfam Interfer-bind 136 227
transmembrane n/a 230 254

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q6UXL0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MQTFTMVLEE IWTSLFMWFF YALIPCLLTD EVAILPAPQN LSVLSTNMKH
50
51
LLMWSPVIAP GETVYYSVEY QGEYESLYTS HIWIPSSWCS LTEGPECDVT
100
101
DDITATVPYN LRVRATLGSQ TSAWSILKHP FNRNSTILTR PGMEITKDGF
150
151
HLVIELEDLG PQFEFLVAYW RREPGAEEHV KMVRSGGIPV HLETMEPGAA
200
201
YCVKAQTFVK AIGRYSAFSQ TECVEVQGEA IPLVLALFAF VGFMLILVVV
250
251
PLFVWKMGRL LQYSCCPVVV LPDTLKITNS PQKLISCRRE EVDACATAVM
300
301
SPEELLRAWI S                                          
311
 

Show the unformatted sequence.

Checksums:
CRC64:FF366D518116D9E3
MD5:85494a287a9700b6c647ecba2e933d1b

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Interfer-bind 136 - 224 6DF3 H 136 - 224 Jmol OpenAstexViewer
136 - 226 4DOH B 136 - 226 Jmol OpenAstexViewer
D 136 - 226 Jmol OpenAstexViewer
Tissue_fac 34 - 124 4DOH B 34 - 124 Jmol OpenAstexViewer
D 34 - 124 Jmol OpenAstexViewer
35 - 124 6DF3 H 35 - 124 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.