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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: MUC6_HUMAN (Q6W4X9)

Summary

This is the summary of UniProt entry MUC6_HUMAN (Q6W4X9).

Description: Mucin-6
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 2439 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 20
low_complexity n/a 5 18
disorder n/a 30 33
disorder n/a 35 36
Pfam VWD 45 193
Pfam C8 231 297
Pfam TIL 302 357
low_complexity n/a 324 335
Pfam VWD 397 550
low_complexity n/a 533 545
Pfam C8 591 660
Pfam TIL 764 827
Pfam VWD 868 1019
Pfam C8 1060 1127
disorder n/a 1196 2081
low_complexity n/a 1197 1212
low_complexity n/a 1223 1236
low_complexity n/a 1230 1241
low_complexity n/a 1244 1264
low_complexity n/a 1293 1329
low_complexity n/a 1323 1338
low_complexity n/a 1351 1366
low_complexity n/a 1358 1385
low_complexity n/a 1379 1414
low_complexity n/a 1520 1556
low_complexity n/a 1562 1589
low_complexity n/a 1589 1610
low_complexity n/a 1686 1711
low_complexity n/a 1706 1726
low_complexity n/a 1717 1733
low_complexity n/a 1726 1747
low_complexity n/a 1740 1767
low_complexity n/a 1793 1815
low_complexity n/a 1815 1841
low_complexity n/a 1872 1882
low_complexity n/a 1890 1916
low_complexity n/a 1962 1982
low_complexity n/a 1982 2003
low_complexity n/a 2040 2050
low_complexity n/a 2070 2091
low_complexity n/a 2088 2099
disorder n/a 2090 2167
low_complexity n/a 2097 2105
low_complexity n/a 2120 2168
disorder n/a 2169 2171
low_complexity n/a 2170 2190
disorder n/a 2176 2200
low_complexity n/a 2189 2204
disorder n/a 2202 2206
disorder n/a 2208 2210
low_complexity n/a 2228 2238
disorder n/a 2239 2280
low_complexity n/a 2264 2282
disorder n/a 2287 2288
disorder n/a 2296 2326
disorder n/a 2329 2351
disorder n/a 2407 2408

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q6W4X9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVQRWLLLSC CGALLSAGLA NTSYTSPGLQ RLKDSPQTAP DKGQCSTWGA
50
51
GHFSTFDHHV YDFSGTCNYI FAATCKDAFP TFSVQLRRGP DGSISRIIVE
100
101
LGASVVTVSE AIISVKDIGV ISLPYTSNGL QITPFGQSVR LVAKQLELEL
150
151
EVVWGPDSHL MVLVERKYMG QMCGLCGNFD GKVTNEFVSE EGKFLEPHKF
200
201
AALQKLDDPG EICTFQDIPS THVRQAQHAR ICTQLLTLVA PECSVSKEPF
250
251
VLSCQADVAA APQPGPQNSS CATLSEYSRQ CSMVGQPVRR WRSPGLCSVG
300
301
QCPANQVYQE CGSACVKTCS NPQHSCSSSC TFGCFCPEGT VLNDLSNNHT
350
351
CVPVTQCPCV LHGAMYAPGE VTIAACQTCR CTLGRWVCTE RPCPGHCSLE
400
401
GGSFVTTFDA RPYRFHGTCT YILLQSPQLP EDGALMAVYD KSGVSHSETS
450
451
LVAVVYLSRQ DKIVISQDEV VTNNGEAKWL PYKTRNITVF RQTSTHLQMA
500
501
TSFGLELVVQ LRPIFQAYVT VGPQFRGQTR GLCGNFNGDT TDDFTTSMGI
550
551
AEGTASLFVD SWRAGNCPAA LERETDPCSM SQLNKVCAET HCSMLLRTGT
600
601
VFERCHATVN PAPFYKRCVY QACNYEETFP HICAALGDYV HACSLRGVLL
650
651
WGWRSSVDNC TIPCTGNTTF SYNSQACERT CLSLSDRATE CHHSAVPVDG
700
701
CNCPDGTYLN QKGECVRKAQ CPCILEGYKF ILAEQSTVIN GITCHCINGR
750
751
LSCPQRPQMF LASCQAPKTF KSCSQSSENK FGAACAPTCQ MLATGVACVP
800
801
TKCEPGCVCA EGLYENADGQ CVPPEECPCE FSGVSYPGGA ELHTDCRTCS
850
851
CSRGRWACQQ GTHCPSTCTL YGEGHVITFD GQRFVFDGNC EYILATDVCG
900
901
VNDSQPTFKI LTENVICGNS GVTCSRAIKI FLGGLSVVLA DRNYTVTGEE
950
951
PHVQLGVTPG ALSLVVDISI PGRYNLTLIW NRHMTILIRI ARASQDPLCG
1000
1001
LCGNFNGNMK DDFETRSRYV ASSELELVNS WKESPLCGDV SFVTDPCSLN
1050
1051
AFRRSWAERK CSVINSQTFA TCHSKVYHLP YYEACVRDAC GCDSGGDCEC
1100
1101
LCDAVAAYAQ ACLDKGVCVD WRTPAFCPIY CGFYNTHTQD GHGEYQYTQE
1150
1151
ANCTWHYQPC LCPSQPQSVP GSNIEGCYNC SQDEYFDHEE GVCVPCMPPT
1200
1201
TPQPPTTPQL PTTGSRPTQV WPMTGTSTTI GLLSSTGPSP SSNHTPASPT
1250
1251
QTPLLPATLT SSKPTASSGE PPRPTTAVTP QATSGLPPTA TLRSTATKPT
1300
1301
VTQATTRATA STASPATTST AQSTTRTTMT LPTPATSGTS PTLPKSTNQE
1350
1351
LPGTTATQTT GPRPTPASTT GPTTPQPGQP TRPTATETTQ TRTTTEYTTP
1400
1401
QTPHTTHSPP TAGSPVPSTG PVTATSFHAT TTYPTPSHPE TTLPTHVPPF
1450
1451
STSLVTPSTH TVITPTHAQM ATSASNHSAP TGTIPPPTTL KATGSTHTAP
1500
1501
PITPTTSGTS QAHSSFSTNK TPTSLHSHTS STHHPEVTPT STTTITPNPT
1550
1551
STRTRTPVAH TNSATSSRPP PPFTTHSPPT GSSPFSSTGP MTATSFKTTT
1600
1601
TYPTPSHPQT TLPTHVPPFS TSLVTPSTHT VITPTHAQMA TSASIHSMPT
1650
1651
GTIPPPTTLK ATGSTHTAPT MTLTTSGTSQ ALSSLNTAKT STSLHSHTSS
1700
1701
THHAEATSTS TTNITPNPTS TGTPPMTVTT SGTSQSRSSF STAKTSTSLH
1750
1751
SHTSSTHHPE VTSTSTTSIT PNHTSTGTRT PVAHTTSATS SRLPTPFTTH
1800
1801
SPPTGTTPIS STGPVTATSF QTTTTYPTPS HPHTTLPTHV PSFSTSLVTP
1850
1851
STHTVIIPTH TQMATSASIH SMPTGTIPPP TTIKATGSTH TAPPMTPTTS
1900
1901
GTSQSPSSFS TAKTSTSLPY HTSSTHHPEV TPTSTTNITP KHTSTGTRTP
1950
1951
VAHTTSASSS RLPTPFTTHS PPTGSSPFSS TGPMTATSFQ TTTTYPTPSH
2000
2001
PQTTLPTHVP PFSTSLVTPS THTVIITTHT QMATSASIHS TPTGTVPPPT
2050
2051
TLKATGSTHT APPMTVTTSG TSQTHSSFST ATASSSFISS SSWLPQNSSS
2100
2101
RPPSSPITTQ LPHLSSATTP VSTTNQLSSS FSPSPSAPST VSSYVPSSHS
2150
2151
SPQTSSPSVG TSSSFVSAPV HSTTLSSGSH SSLSTHPTTA SVSASPLFPS
2200
2201
SPAASTTIRA TLPHTISSPF TLSALLPIST VTVSPTPSSH LASSTIAFPS
2250
2251
TPRTTASTHT APAFSSQSTT SRSTSLTTRV PTSGFVSLTS GVTGIPTSPV
2300
2301
TNLTTRHPGP TLSPTTRFLT SSLTAHGSTP ASAPVSSLGT PTPTSPGVCS
2350
2351
VREQQEEITF KGCMANVTVT RCEGACISAA SFNIITQQVD ARCSCCRPLH
2400
2401
SYEQQLELPC PDPSTPGRRL VLTLQVFSHC VCSSVACGD            
2439
 

Show the unformatted sequence.

Checksums:
CRC64:4A1A7E6A7C30F895
MD5:78d1a7f9d2f26d5d1efa9f726ab16cda

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.