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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TMPPE_HUMAN (Q6ZT21)

Summary

This is the summary of UniProt entry TMPPE_HUMAN (Q6ZT21).

Description: Transmembrane protein with metallophosphoesterase domain EC=3.1.-.-
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 453 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
transmembrane n/a 7 26
low_complexity n/a 34 49
transmembrane n/a 46 64
transmembrane n/a 84 106
transmembrane n/a 112 135
transmembrane n/a 162 182
Pfam Metallophos 207 395
disorder n/a 306 319
low_complexity n/a 314 322

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q6ZT21. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAIFRQLSLG AKATLAAVTV FVSMIASRSY LAESLELRAW RWLLRLQLAL
50
51
FVNSLLLIGS LYIWRSTVSN LCHSPAAEST CFQLWKVVVL AFLALAHSSF
100
101
FTMFFLVAEE PYLFSLAAYS CLGAYIIMLF FLFILSGMEQ AYQLLAWRSG
150
151
RVVGSLEKTR KLVLRPALAV GVTAVLSVAG ILNAAQPPAV KTVEVPIHQL
200
201
PASMNNLKIV LLSDIHLGPT VGRTKMEMFV RMVNVLEPDI TVIVGDLSDS
250
251
EASVLRTAVA PLGQLHSHLG AYFVTGNHEY YTSDVSNWFA LLESLHVQPL
300
301
HNENVKISAT RAQRGGGGSG SGSEDEDWIC LAGVDDIEAD ILHYSGHGMD
350
351
LDKALEGCSP DHTIILLAHQ PLAAKRALQA RPDINLILSG HTHAGQIFPL
400
401
NVAAYLLNPF FAGLYQVAQA TFVYVSPGTA YYGIPMRLGS RAEITELILQ
450
451
RSP                                                   
453
 

Show the unformatted sequence.

Checksums:
CRC64:F5455B6801793D68
MD5:2631f6b3301fe0b3e6f1849877781b91

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.