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4  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q72547_9HIV1 (Q72547)

Summary

This is the summary of UniProt entry Q72547_9HIV1 (Q72547).

Description: Reverse transcriptase/RNaseH {ECO:0000313|EMBL:AAA93161.1} (Fragment)
Source organism: Human immunodeficiency virus 1 (NCBI taxonomy ID )
Length: 566 amino acids
Reference Proteome: x

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam RVT_1 63 234
Pfam RVT_thumb 241 304
Pfam RVT_connect 318 419
Pfam RNase_H 436 557

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q72547. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
PISPIETVPV KLKPGMDGPK VKQWPLTEEK IKALVEICTE MEKEGKISKI
50
51
GPENPYNTPV FAIKKKDSTK WRKLVDFREL NKRTQDFWEV QLGIPHPAGL
100
101
KKRKSVTVLD VGDAYFSVPL DEDFRKYTAF TIPSINNETP GIRYQYNVLP
150
151
QGWKGSPAIF QSSMTKILEP FRKQNPDIVI YQYMDDLYVG SDLEIGQHRT
200
201
KIEELRQHLL RWGLTTPDKK HQKEPPFLWM GYELHPDKWT VQPIVLPEKD
250
251
SWTVNDIQKL VGKLNWASQI YPGIRVRQLC KLLRGTKALT EVIPLTEEAE
300
301
LELAENREIL KEPVHGVYYD PSKDLIAEIQ KQGQGQWTYQ IYQEPFKNLR
350
351
TGKYARMRGA HTNDVKQLTE AVQKITTESI VIWGKTPKFK LPIQKETWET
400
401
WWTEYWQATW IPEWEFVNTP PLVKLWYQLE KEPIVGAETF YVDGAANRET
450
451
KLGKAGYVTN RGRQKVVTLT DTTNQKTELQ AIYLALQDSG LEVNIVTDSQ
500
501
YALGIIQAQP DQSESELVNQ IIEQLIKKEK VYLAWVPAHK GIGGNEQVDK
550
551
LVSAGIRKVL FLDGID                                     
566
 

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Checksums:
CRC64:AA4B9287ECC4E5C6
MD5:347541fa98e55ebf1791ded88f229d8c

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
RNase_H 436 - 545 2JLE A 436 - 545 Jmol OpenAstexViewer
436 - 557 3HYF A 436 - 557 Jmol OpenAstexViewer
3QIN A 436 - 557 Jmol OpenAstexViewer
3QIO A 436 - 557 Jmol OpenAstexViewer
RVT_1 63 - 234 2JLE A 63 - 234 Jmol OpenAstexViewer
B 63 - 234 Jmol OpenAstexViewer
RVT_connect 318 - 419 2JLE A 318 - 419 Jmol OpenAstexViewer
B 318 - 419 Jmol OpenAstexViewer
RVT_thumb 241 - 304 2JLE A 241 - 304 Jmol OpenAstexViewer
B 241 - 304 Jmol OpenAstexViewer