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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CLAP1_HUMAN (Q7Z460)

Summary

This is the summary of UniProt entry CLAP1_HUMAN (Q7Z460).

Description: CLIP-associating protein 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 1538 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam HEAT 168 198
disorder n/a 231 285
low_complexity n/a 250 267
low_complexity n/a 283 295
disorder n/a 287 291
Pfam CLASP_N 320 537
disorder n/a 543 793
low_complexity n/a 547 567
low_complexity n/a 573 593
low_complexity n/a 605 627
low_complexity n/a 672 689
low_complexity n/a 682 708
low_complexity n/a 752 764
disorder n/a 795 796
disorder n/a 804 807
disorder n/a 815 823
low_complexity n/a 822 832
disorder n/a 827 828
disorder n/a 833 835
disorder n/a 837 838
disorder n/a 1075 1077
disorder n/a 1080 1118
low_complexity n/a 1097 1114
disorder n/a 1129 1130
disorder n/a 1133 1136
disorder n/a 1138 1170
disorder n/a 1172 1180
disorder n/a 1190 1264
low_complexity n/a 1226 1237
disorder n/a 1267 1269
coiled_coil n/a 1308 1328
low_complexity n/a 1347 1351
coiled_coil n/a 1390 1410
low_complexity n/a 1405 1416
low_complexity n/a 1522 1537
disorder n/a 1527 1538

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q7Z460. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEPRMESCLA QVLQKDVGKR LQVGQELIDY FSDKQKSADL EHDQTMLDKL
50
51
VDGLATSWVN SSNYKVVLLG MDILSALVTR LQDRFKAQIG TVLPSLIDRL
100
101
GDAKDSVREQ DQTLLLKIMD QAANPQYVWD RMLGGFKHKN FRTREGICLC
150
151
LIATLNASGA QTLTLSKIVP HICNLLGDPN SQVRDAAINS LVEIYRHVGE
200
201
RVRADLSKKG LPQSRLNVIF TKFDEVQKSG NMIQSANDKN FDDEDSVDGN
250
251
RPSSASSTSS KAPPSSRRNV GMGTTRRLGS STLGSKSSAA KEGAGAVDEE
300
301
DFIKAFDDVP VVQIYSSRDL EESINKIREI LSDDKHDWEQ RVNALKKIRS
350
351
LLLAGAAEYD NFFQHLRLLD GAFKLSAKDL RSQVVREACI TLGHLSSVLG
400
401
NKFDHGAEAI MPTIFNLIPN SAKIMATSGV VAVRLIIRHT HIPRLIPVIT
450
451
SNCTSKSVAV RRRCFEFLDL LLQEWQTHSL ERHISVLAET IKKGIHDADS
500
501
EARIEARKCY WGFHSHFSRE AEHLYHTLES SYQKALQSHL KNSDSIVSLP
550
551
QSDRSSSSSQ ESLNRPLSAK RSPTGSTTSR ASTVSTKSVS TTGSLQRSRS
600
601
DIDVNAAASA KSKVSSSSGT TPFSSAAALP PGSYASLGRI RTRRQSSGSA
650
651
TNVASTPDNR GRSRAKVVSQ SQRSRSANPA GAGSRSSSPG KLLGSGYGGL
700
701
TGGSSRGPPV TPSSEKRSKI PRSQGCSRET SPNRIGLARS SRIPRPSMSQ
750
751
GCSRDTSRES SRDTSPARGF PPLDRFGLGQ PGRIPGSVNA MRVLSTSTDL
800
801
EAAVADALKK PVRRRYEPYG MYSDDDANSD ASSVCSERSY GSRNGGIPHY
850
851
LRQTEDVAEV LNHCASSNWS ERKEGLLGLQ NLLKSQRTLS RVELKRLCEI
900
901
FTRMFADPHS KRVFSMFLET LVDFIIIHKD DLQDWLFVLL TQLLKKMGAD
950
951
LLGSVQAKVQ KALDVTRDSF PFDQQFNILM RFIVDQTQTP NLKVKVAILK
1000
1001
YIESLARQMD PTDFVNSSET RLAVSRIITW TTEPKSSDVR KAAQIVLISL
1050
1051
FELNTPEFTM LLGALPKTFQ DGATKLLHNH LKNSSNTSVG SPSNTIGRTP
1100
1101
SRHTSSRTSP LTSPTNCSHG GLSPSRLWGW SADGLAKHPP PFSQPNSIPT
1150
1151
APSHKALRRS YSPSMLDYDT ENLNSEEIYS SLRGVTEAIE KFSFRSQEDL
1200
1201
NEPIKRDGKK ECDIVSRDGG AASPATEGRG GSEVEGGRTA LDNKTSLLNT
1250
1251
QPPRAFPGPR ARDYNPYPYS DAINTYDKTA LKEAVFDDDM EQLRDVPIDH
1300
1301
SDLVADLLKE LSNHNERVEE RKGALLELLK ITREDSLGVW EEHFKTILLL
1350
1351
LLETLGDKDH SIRALALRVL REILRNQPAR FKNYAELTIM KTLEAHKDSH
1400
1401
KEVVRAAEEA ASTLASSIHP EQCIKVLCPI IQTADYPINL AAIKMQTKVV
1450
1451
ERIAKESLLQ LLVDIIPGLL QGYDNTESSV RKASVFCLVA IYSVIGEDLK
1500
1501
PHLAQLTGSK MKLLNLYIKR AQTTNSNSSS SSDVSTHS             
1538
 

Show the unformatted sequence.

Checksums:
CRC64:6E03BD948C227F8D
MD5:1c295dd9bcc5c4336b2deffae3f152b3

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
CLASP_N 320 - 537 4K92 A 320 - 537 Jmol OpenAstexViewer
B 320 - 537 Jmol OpenAstexViewer
6MQ7 A 320 - 537 Jmol OpenAstexViewer
B 320 - 537 Jmol OpenAstexViewer
HEAT 168 - 198 6MQ5 A 168 - 198 Jmol OpenAstexViewer
B 168 - 198 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.