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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: GDF7_HUMAN (Q7Z4P5)

Summary

This is the summary of UniProt entry GDF7_HUMAN (Q7Z4P5).

Description: Growth/differentiation factor 7
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 450 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 19
low_complexity n/a 2 16
low_complexity n/a 24 37
low_complexity n/a 29 79
disorder n/a 36 50
Pfam TGFb_propeptide 66 280
disorder n/a 78 79
low_complexity n/a 96 117
disorder n/a 108 112
disorder n/a 118 133
disorder n/a 135 136
disorder n/a 159 162
disorder n/a 165 170
low_complexity n/a 168 186
disorder n/a 173 177
disorder n/a 215 219
low_complexity n/a 217 227
low_complexity n/a 250 258
disorder n/a 264 268
low_complexity n/a 284 295
disorder n/a 295 346
low_complexity n/a 314 329
low_complexity n/a 324 350
Pfam TGF_beta 347 449
disorder n/a 348 349

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q7Z4P5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDLSAAAALC LWLLSACRPR DGLEAAAVLR AAGAGPVRSP GGGGGGGGGG
50
51
RTLAQAAGAA AVPAAAVPRA RAARRAAGSG FRNGSVVPHH FMMSLYRSLA
100
101
GRAPAGAAAV SASGHGRADT ITGFTDQATQ DESAAETGQS FLFDVSSLND
150
151
ADEVVGAELR VLRRGSPESG PGSWTSPPLL LLSTCPGAAR APRLLYSRAA
200
201
EPLVGQRWEA FDVADAMRRH RREPRPPRAF CLLLRAVAGP VPSPLALRRL
250
251
GFGWPGGGGS AAEERAVLVV SSRTQRKESL FREIRAQARA LGAALASEPL
300
301
PDPGTGTASP RAVIGGRRRR RTALAGTRTA QGSGGGAGRG HGRRGRSRCS
350
351
RKPLHVDFKE LGWDDWIIAP LDYEAYHCEG LCDFPLRSHL EPTNHAIIQT
400
401
LLNSMAPDAA PASCCVPARL SPISILYIDA ANNVVYKQYE DMVVEACGCR
450
451
                                                      
450
 

Show the unformatted sequence.

Checksums:
CRC64:C7D4D417685D25BD
MD5:b281405a642954cac2790d92b47cc65b

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.