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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DCXR_HUMAN (Q7Z4W1)

Summary

This is the summary of UniProt entry DCXR_HUMAN (Q7Z4W1).

Description: L-xylulose reductase EC=1.1.1.10
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 244 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam adh_short_C2 14 242
low_complexity n/a 78 88

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q7Z4W1. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MELFLAGRRV LVTGAGKGIG RGTVQALHAT GARVVAVSRT QADLDSLVRE
50
51
CPGIEPVCVD LGDWEATERA LGSVGPVDLL VNNAAVALLQ PFLEVTKEAF
100
101
DRSFEVNLRA VIQVSQIVAR GLIARGVPGA IVNVSSQCSQ RAVTNHSVYC
150
151
STKGALDMLT KVMALELGPH KIRVNAVNPT VVMTSMGQAT WSDPHKAKTM
200
201
LNRIPLGKFA EVEHVVNAIL FLLSDRSGMT TGSTLPVEGG FWAC      
244
 

Show the unformatted sequence.

Checksums:
CRC64:F82B7A178D46EAA5
MD5:23b85f42831bcb2cf8231e9c35081628

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
adh_short_C2 14 - 242 1PR9 A 14 - 242 Jmol OpenAstexViewer
B 14 - 242 Jmol OpenAstexViewer
1WNT A 14 - 242 Jmol OpenAstexViewer
B 14 - 242 Jmol OpenAstexViewer
C 14 - 242 Jmol OpenAstexViewer
D 14 - 242 Jmol OpenAstexViewer
3D3W A 14 - 242 Jmol OpenAstexViewer
B 14 - 242 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.