Summary
This is the summary of UniProt entry ADAT2_HUMAN (Q7Z6V5).
Description: | tRNA-specific adenosine deaminase 2 |
Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
Length: | 191 amino acids |
Reference Proteome: |
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Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
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Source | Domain | Start | End |
---|---|---|---|
disorder | n/a | 1 | 3 |
low_complexity | n/a | 2 | 10 |
disorder | n/a | 10 | 13 |
disorder | n/a | 16 | 17 |
Pfam | dCMP_cyt_deam_1 | 19 | 126 |
disorder | n/a | 28 | 32 |
disorder | n/a | 60 | 68 |
disorder | n/a | 181 | 186 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q7Z6V5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
Sequence: | 1
MEAKAAPKPA ASGACSVSAE ETEKWMEEAM HMAKEALENT EVPVGCLMVY
50 51
NNEVVGKGRN EVNQTKNATR HAEMVAIDQV LDWCRQSGKS PSEVFEHTVL
100 101
YVTVEPCIMC AAALRLMKIP LVVYGCQNER FGGCGSVLNI ASADLPNTGR
150 151
PFQCIPGYRA EEAVEMLKTF YKQENPNAPK SKVRKKECQK S
191
Show the unformatted sequence. |
Checksums: |
CRC64:7F2881A100A1782E
MD5:12aeb4402052c84802d242fd45ea1abe
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
---|---|---|---|---|---|
dCMP_cyt_deam_1 | 20 - 126 | 3DH1 | A | 20 - 126 | Jmol OpenAstexViewer |
B | 20 - 126 | Jmol OpenAstexViewer | |||
C | 20 - 126 | Jmol OpenAstexViewer | |||
D | 20 - 126 | Jmol OpenAstexViewer |
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.