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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TTC7B_HUMAN (Q86TV6)

Summary

This is the summary of UniProt entry TTC7B_HUMAN (Q86TV6).

Description: Tetratricopeptide repeat protein 7B
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 843 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 5
disorder n/a 8 9
disorder n/a 59 79
disorder n/a 198 199
disorder n/a 201 206
disorder n/a 209 210
disorder n/a 289 295
disorder n/a 298 299
low_complexity n/a 328 332
Pfam TPR_8 397 430
Pfam ANAPC3 494 575
low_complexity n/a 550 560
disorder n/a 630 632
disorder n/a 679 680
Pfam TPR_12 728 795
Pfam TPR_8 798 831

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q86TV6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MATKKAGSRL ETEIERCRSE CQWERIPELV KQLSAKLIAN DDMAELLLGE
50
51
SKLEQYLKEH PLRQGASPRG PKPQLTEVRK HLTAALDRGN LKSEFLQESN
100
101
LIMAKLNYVE GDYKEALNIY ARVGLDDLPL TAVPPYRLRV IAEAYATKGL
150
151
CLEKLPISSS TSNLHVDREQ DVITCYEKAG DIALLYLQEI ERVILSNIQN
200
201
RSPKPGPAPH DQELGFFLET GLQRAHVLYF KNGNLTRGVG RFRELLRAVE
250
251
TRTTQNLRMT IARQLAEILL RGMCEQSYWN PLEDPPCQSP LDDPLRKGAN
300
301
TKTYTLTRRA RVYSGENIFC PQENTEEALL LLLISESMAN RDAVLSRIPE
350
351
HKSDRLISLQ SASVVYDLLT IALGRRGQYE MLSECLERAM KFAFEEFHLW
400
401
YQFALSLMAA GKSARAVKVL KECIRLKPDD ATIPLLAAKL CMGSLHWLEE
450
451
AEKFAKTVVD VGEKTSEFKA KGYLALGLTY SLQATDASLR GMQEVLQRKA
500
501
LLAFQRAHSL SPTDHQAAFY LALQLAISRQ IPEALGYVRQ ALQLQGDDAN
550
551
SLHLLALLLS AQKHYHDALN IIDMALSEYP ENFILLFSKV KLQSLCRGPD
600
601
EALLTCKHML QIWKSCYNLT NPSDSGRGSS LLDRTIADRR QLNTITLPDF
650
651
SDPETGSVHA TSVAASRVEQ ALSEVASSLQ SSAPKQGPLH PWMTLAQIWL
700
701
HAAEVYIGIG KPAEATACTQ EAANLFPMSH NVLYMRGQIA ELRGSMDEAR
750
751
RWYEEALAIS PTHVKSMQRL ALILHQLGRY SLAEKILRDA VQVNSTAHEV
800
801
WNGLGEVLQA QGNDAAATEC FLTALELEAS SPAVPFTIIP RVL       
843
 

Show the unformatted sequence.

Checksums:
CRC64:ADAB8B36878AABDA
MD5:f7b1ecb6c8c9c7f0c7fc19546a9721a9

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
ANAPC3 494 - 575 5DSE A 494 - 575 Jmol OpenAstexViewer
C 494 - 575 Jmol OpenAstexViewer
6BQ1 B 494 - 575 Jmol OpenAstexViewer
F 494 - 575 Jmol OpenAstexViewer
TPR_12 728 - 795 5DSE A 728 - 795 Jmol OpenAstexViewer
C 728 - 795 Jmol OpenAstexViewer
6BQ1 B 728 - 795 Jmol OpenAstexViewer
F 728 - 795 Jmol OpenAstexViewer
TPR_8 397 - 430 5DSE A 397 - 430 Jmol OpenAstexViewer
C 397 - 430 Jmol OpenAstexViewer
6BQ1 B 397 - 430 Jmol OpenAstexViewer
F 397 - 430 Jmol OpenAstexViewer
798 - 831 5DSE A 798 - 831 Jmol OpenAstexViewer
C 798 - 831 Jmol OpenAstexViewer
6BQ1 B 798 - 831 Jmol OpenAstexViewer
F 798 - 831 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.