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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: OAF_HUMAN (Q86UD1)

Summary

This is the summary of UniProt entry OAF_HUMAN (Q86UD1).

Description: Out at first protein homolog
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 273 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 29
low_complexity n/a 3 32
Pfam OAF 30 268
disorder n/a 54 56
disorder n/a 114 115
disorder n/a 122 125

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q86UD1. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MRLPGVPLAR PALLLLLPLL APLLGTGAPA ELRVRVRLPD GQVTEESLQA
50
51
DSDADSISLE LRKPDGTLVS FTADFKKDVK VFRALILGEL EKGQSQFQAL
100
101
CFVTQLQHNE IIPSEAMAKL RQKNPRAVRQ AEEVRGLEHL HMDVAVNFSQ
150
151
GALLSPHLHN VCAEAVDAIY TRQEDVRFWL EQGVDSSVFE ALPKASEQAE
200
201
LPRCRQVGDH GKPCVCRYGL SLAWYPCMLK YCHSRDRPTP YKCGIRSCQK
250
251
SYSFDFYVPQ RQLCLWDEDP YPG                             
273
 

Show the unformatted sequence.

Checksums:
CRC64:EC752B522917F496
MD5:e6e5e5c9032cefe2b7843727a0f1d45c

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;