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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: LONP2_HUMAN (Q86WA8)

Summary

This is the summary of UniProt entry LONP2_HUMAN (Q86WA8).

Description: Lon protease homolog 2, peroxisomal {ECO:0000255|HAMAP-Rule:MF_03121}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 852 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam LON_substr_bdg 12 220
disorder n/a 63 64
disorder n/a 67 73
disorder n/a 256 259
low_complexity n/a 258 268
disorder n/a 269 270
disorder n/a 272 274
Pfam AAA 371 512
low_complexity n/a 487 499
disorder n/a 537 538
low_complexity n/a 537 544
disorder n/a 586 609
disorder n/a 611 617
Pfam Lon_C 628 837
low_complexity n/a 680 689

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q86WA8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSSVSPIQIP SRLPLLLTHE GVLLPGSTMR TSVDSARNLQ LVRSRLLKGT
50
51
SLQSTILGVI PNTPDPASDA QDLPPLHRIG TAALAVQVVG SNWPKPHYTL
100
101
LITGLCRFQI VQVLKEKPYP IAEVEQLDRL EEFPNTCKMR EELGELSEQF
150
151
YKYAVQLVEM LDMSVPAVAK LRRLLDSLPR EALPDILTSI IRTSNKEKLQ
200
201
ILDAVSLEER FKMTIPLLVR QIEGLKLLQK TRKPKQDDDK RVIAIRPIRR
250
251
ITHISGTLED EDEDEDNDDI VMLEKKIRTS SMPEQAHKVC VKEIKRLKKM
300
301
PQSMPEYALT RNYLELMVEL PWNKSTTDRL DIRAARILLD NDHYAMEKLK
350
351
KRVLEYLAVR QLKNNLKGPI LCFVGPPGVG KTSVGRSVAK TLGREFHRIA
400
401
LGGVCDQSDI RGHRRTYVGS MPGRIINGLK TVGVNNPVFL LDEVDKLGKS
450
451
LQGDPAAALL EVLDPEQNHN FTDHYLNVAF DLSQVLFIAT ANTTATIPAA
500
501
LLDRMEIIQV PGYTQEEKIE IAHRHLIPKQ LEQHGLTPQQ IQIPQVTTLD
550
551
IITRYTREAG VRSLDRKLGA ICRAVAVKVA EGQHKEAKLD RSDVTEREGC
600
601
REHILEDEKP ESISDTTDLA LPPEMPILID FHALKDILGP PMYEMEVSQR
650
651
LSQPGVAIGL AWTPLGGEIM FVEASRMDGE GQLTLTGQLG DVMKESAHLA
700
701
ISWLRSNAKK YQLTNAFGSF DLLDNTDIHL HFPAGAVTKD GPSAGVTIVT
750
751
CLASLFSGRL VRSDVAMTGE ITLRGLVLPV GGIKDKVLAA HRAGLKQVII
800
801
PRRNEKDLEG IPGNVRQDLS FVTASCLDEV LNAAFDGGFT VKTRPGLLNS
850
851
KL                                                    
852
 

Show the unformatted sequence.

Checksums:
CRC64:00444E4FF47417AC
MD5:5e4cdf11a944fa8551091d66a3e98bc1

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.