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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: LDHD_HUMAN (Q86WU2)

Summary

This is the summary of UniProt entry LDHD_HUMAN (Q86WU2).

Description: Probable D-lactate dehydrogenase, mitochondrial EC=1.1.2.4
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 507 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 55 57
disorder n/a 61 63
Pfam FAD_binding_4 66 203
low_complexity n/a 102 113
Pfam FAD-oxidase_C 265 506
disorder n/a 339 342

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q86WU2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MARLLRSATW ELFPWRGYCS QKAKGELCRD FVEALKAVVG GSHVSTAAVV
50
51
REQHGRDESV HRCEPPDAVV WPQNVEQVSR LAALCYRQGV PIIPFGTGTG
100
101
LEGGVCAVQG GVCVNLTHMD RILELNQEDF SVVVEPGVTR KALNAHLRDS
150
151
GLWFPVDPGA DASLCGMAAT GASGTNAVRY GTMRDNVLNL EVVLPDGRLL
200
201
HTAGRGRHFR FGFWPEIPHH TAWYSPCVSL GRRKSAAGYN LTGLFVGSEG
250
251
TLGLITATTL RLHPAPEATV AATCAFPSVQ AAVDSTVHIL QAAVPVARIE
300
301
FLDEVMMDAC NRYSKLNCLV APTLFLEFHG SQQALEEQLQ RTEEIVQQNG
350
351
ASDFSWAKEA EERSRLWTAR HNAWYAALAT RPGCKGYSTD VCVPISRLPE
400
401
IVVQTKEDLN ASGLTGSIVG HVGDGNFHCI LLVNPDDAEE LGRVKAFAEQ
450
451
LGRRALALHG TCTGEHGIGM GKRQLLQEEV GAVGVETMRQ LKAVLDPQGL
500
501
MNPGKVL                                               
507
 

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Checksums:
CRC64:5625743709939182
MD5:9a9454133781052df8ceabe8d12a4401

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.