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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PDPN_HUMAN (Q86YL7)

Summary

This is the summary of UniProt entry PDPN_HUMAN (Q86YL7).

Description: Podoplanin {ECO:0000303|Ref.9}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 162 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 22
disorder n/a 20 57
Pfam Podoplanin 28 161
disorder n/a 83 122
low_complexity n/a 128 145
transmembrane n/a 131 153
low_complexity n/a 136 151

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q86YL7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MWKVSALLFV LGSASLWVLA EGASTGQPED DTETTGLEGG VAMPGAEDDV
50
51
VTPGTSEDRY KSGLTTLVAT SVNSVTGIRI EDLPTSESTV HAQEQSPSAT
100
101
ASNVATSHST EKVDGDTQTT VEKDGLSTVT LVGIIVGVLL AIGFIGAIIV
150
151
VVMRKMSGRY SP                                         
162
 

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Checksums:
CRC64:CD96D46FF5BD56A1
MD5:ce6bf63d7c9b39832f5a877f77249d50

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Podoplanin 40 - 50 5XCV C 3 - 13 Jmol OpenAstexViewer
40 - 51 4YO0 E 3 - 14 Jmol OpenAstexViewer
41 - 51 4YO0 F 4 - 14 Jmol OpenAstexViewer
42 - 50 5XCV F 5 - 13 Jmol OpenAstexViewer
45 - 54 3WSR D 45 - 54 Jmol OpenAstexViewer
46 - 54 3WSR C 46 - 54 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.