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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CPNE8_HUMAN (Q86YQ8)

Summary

This is the summary of UniProt entry CPNE8_HUMAN (Q86YQ8).

Description: Copine-8 {ECO:0000305}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 564 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam C2 25 135
Pfam C2 159 267
low_complexity n/a 271 278
Pfam Copine 328 547
disorder n/a 546 561
low_complexity n/a 546 556

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q86YQ8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDSRYNSTAG IGDLNQLSAA IPATRVEVSV SCRNLLDRDT FSKSDPICVL
50
51
YVQGVGNKEW REFGRTEVID NTLNPDFVRK FILDYFFEER ENLRFDLYDV
100
101
DSKSPNLSKH DFLGQVFCTL GEIVGSQGSR LEKPIVGIPG KKCGTIILTA
150
151
EELNCCRDAV LMQFCANKLD KKDFFGKSDP FLVFYRSNED GSFTICHKTE
200
201
VVKNTLNPVW QAFKISVRAL CNGDYDRTIK VEVYDWDRDG SHDFIGEFTT
250
251
SYRELSRGQS QFNVYEVVNP KKKGKKKKYT NSGTVTLLSF LVETEVSFLD
300
301
YIKGGTQINF TVAIDFTASN GNPAQPTSLH YMNPYQLNAY GMALKAVGEI
350
351
VQDYDSDKMF PALGFGAKLP PDGRISHEFA LNGNPQNPYC DGIEGVMEAY
400
401
YRSLKSVQLY GPTNFAPVIN HVARYASSVK DGSQYFVLLI VTDGVISDMA
450
451
QTKESIVNAS KLPMSIIIVG VGPAEFDAMV ELDGDDVRVS SRGKYAERDI
500
501
VQFVPFRDYI DRSGNHILSM ARLAKDVLAE IPEQFLSYMR ARGIKPSPAP
550
551
PPYTPPTHVL QTQI                                       
564
 

Show the unformatted sequence.

Checksums:
CRC64:BD12DAA905F03692
MD5:3f5b6f76d0db37241c65932c3e25b06c

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;