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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DEN6A_MOUSE (Q8BH65)

Summary

This is the summary of UniProt entry DEN6A_MOUSE (Q8BH65).

Description: Protein DENND6A
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 605 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 14 16
low_complexity n/a 17 45
low_complexity n/a 37 51
Pfam Avl9 59 200
disorder n/a 244 247
Pfam SPA 265 373
low_complexity n/a 379 390
low_complexity n/a 412 423
disorder n/a 417 419
low_complexity n/a 526 541
low_complexity n/a 554 563

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8BH65. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MALPGPAVFG PGSRGSLDEA GAEGREAAAL AAAGVALEDE EEDDGRRGLL
50
51
RWDGFSAWLH CVCVVGFDLE LGQAVEVIYP QHSKLTDKEK TNICYLSFPD
100
101
SNSGCLGDTQ FCFRFRQSSG RRVSLHCLLD EFDKDLPVYL KKDPAYFYGY
150
151
VYFRQVRDKT LKRGYFQKSL VLISKLPYIH FFHTVLKQIA PEYFEKNEPY
200
201
LEAACNDVDR WPAPVPGKTL HLPIMGLVMK VRIPTCHDKP GTTQMVQLTQ
250
251
QADTHTSIIL PTVHEVDLFR CFCPVFLHSQ MLWELVLLGE PLVVMAPSPS
300
301
ESSETVLALV NCISPLKYFS DFRPYFTIHD SEFKEYTTRT QAPPSVILGV
350
351
TNPFFAKTLQ HWPHIIRIGD LKPAGEIPKQ VKVKKLKNLK TLDSKPGVYT
400
401
SYKPYLNRDE EIIKQLQKGI QQKRPSEAQS VILRRYFLEL TQSFIIPLER
450
451
YVASLMPLQK SISPWKSPPQ LRQFLPEEFM KTLEKTGPQL TSGIKGDWIG
500
501
LYRQFLKSPN FDGWFKTRRK EMTQKLEALH LEALCEEDLL LWIQKHTEVE
550
551
TVDLVLKLKN KLLQAGRESL PVKPDTVEKL RTHIDAIILA LPDDLQGILL
600
601
KTGMT                                                 
605
 

Show the unformatted sequence.

Checksums:
CRC64:4745B81A08B08FEE
MD5:b02cda5d3702179280dc780d32a1f01a

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;