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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q8IIS3_PLAF7 (Q8IIS3)

Summary

This is the summary of UniProt entry Q8IIS3_PLAF7 (Q8IIS3).

Description: Mechanosensitive ion channel protein, putative {ECO:0000313|EMBL:CZT98745.1}
Source organism: Plasmodium falciparum (isolate 3D7) (NCBI taxonomy ID 36329)
Length: 1812 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
disorder n/a 1 5
disorder n/a 7 9
disorder n/a 53 61
low_complexity n/a 55 72
low_complexity n/a 68 79
transmembrane n/a 87 105
low_complexity n/a 97 108
transmembrane n/a 125 154
low_complexity n/a 204 210
transmembrane n/a 234 260
disorder n/a 439 473
low_complexity n/a 446 461
disorder n/a 478 479
disorder n/a 485 653
low_complexity n/a 506 512
low_complexity n/a 588 604
coiled_coil n/a 620 647
low_complexity n/a 620 648
low_complexity n/a 653 672
disorder n/a 657 658
disorder n/a 664 667
disorder n/a 674 702
disorder n/a 705 719
disorder n/a 725 727
disorder n/a 769 770
disorder n/a 773 810
low_complexity n/a 789 808
disorder n/a 823 831
disorder n/a 833 837
disorder n/a 862 867
disorder n/a 869 898
low_complexity n/a 888 899
disorder n/a 904 908
disorder n/a 942 958
low_complexity n/a 948 964
disorder n/a 968 969
low_complexity n/a 971 988
disorder n/a 976 994
transmembrane n/a 1160 1181
Pfam MS_channel 1162 1367
low_complexity n/a 1168 1185
transmembrane n/a 1188 1207
low_complexity n/a 1238 1253
disorder n/a 1389 1417
low_complexity n/a 1391 1421
disorder n/a 1419 1467
disorder n/a 1469 1509
disorder n/a 1511 1543
disorder n/a 1550 1603
low_complexity n/a 1550 1577
low_complexity n/a 1573 1605
disorder n/a 1613 1614
disorder n/a 1622 1624
disorder n/a 1626 1658
low_complexity n/a 1634 1657
low_complexity n/a 1649 1672
disorder n/a 1690 1691
disorder n/a 1695 1726
low_complexity n/a 1704 1723
disorder n/a 1728 1730
low_complexity n/a 1776 1787

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8IIS3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNEEKDENLK PFSRSKYPQS LMIDMSRSYM TKQDRINALN LYIQKSSYNP
50
51
QLLQDDEEED DEGESETIGD IILRILSIIF PDVSPGLWFF IHFIMNLIVL
100
101
CVSLSSLSEP NVHDPISEPK YNRKFIYGSM YCSFLILGIN IASFSILMSL
150
151
HAIVQKFILE KLLQPSALCA AFYNTVDPEL VYLFWSSIQI IYWRTNIILK
200
201
SDSNENNNNN YYILRIFGYK DDETPFMFLK NIHWLITFPI LLYIVFAVRL
250
251
LFLSIISFIF ELGFLMNAHD LLGKYLRKYG VLRKFNIEWF MFVADKQENI
300
301
RTLFGYELYQ DERIMKQIER DDISKKFIQN TAELLLFKNL PRNCTCCKIT
350
351
INRNKKNTMK LLLPPVFEAK NIIKSESSSL KNWLACHYVV NTPPLLFLLN
400
401
NSIALTNKNS IRNASDIFFR QIIMSLKIYY QEKNDTYAFT TTPIHNNNNN
450
451
NNNNNNNNNN NISMDGLSPH SNILNINTNE KNQFFLKHKK TFPSKTNPNK
500
501
VIPQEKFKKK KKNFHTYDSS DDDRQKKINL ENIFHDVDTY DTKDEGTKDE
550
551
NLTDQDKTSH HMIYEQNIQK IQSIKLSENI NKNKKRDTSK NKSKQTSKTK
600
601
KKKNIPGEHM NHMGKMSQTK KENDKNVEEQ NEQKKKKKDK MDNLKVKNQM
650
651
IHIEKENYNV NNVKIINNDI TNEISDTTMN IIKQDQINEK QNYDIITKTK
700
701
ENLMNNSDKG NIDILPNEKY NVDKHIHNIN VDKDIKDGCH FYDMTNSNMN
750
751
DTKFNILITP SFSTIQNKKD INDTCEKDYT SNKMNKIKNN DDNNDNNNDN
800
801
NNDDDNNNII ICEDEINHEL KYNIKGGDKE EYSNQLENYN SIAVQINDFN
850
851
IDDVLKKKYT NESIHKMEKN SFEDNDIMIP KNNEILQNGN NEIWHNNNNI
900
901
KKEDAYDDYL EDKDNKKDNF HFNEIPLLGG FLFKRNEESV DGNISNMNKN
950
951
SCNEEDMNNN ENIEYHIPFY KKKKEKSGRK LKSSGKEKHT YEINKGNKNI
1000
1001
KNRWSLNKNT YYYHSHLLNE EMNILERSDA INVKRYREEH NKDRYKVCKK
1050
1051
MFRCLFCKRY KKEERLDKIR KDISSDLEDP FVMNVKSPIQ LTLSGNEYIT
1100
1101
KDMIEVFLKP EETEEFMKEF DLSGHGKIDI IMFRNAIKRA ISCRKKFIKS
1150
1151
LKGQESILKL VRRLMSILLS FLASVVLLFL FGVSADTIIV TGAAFITAVT
1200
1201
VILSYMYTNF ITSVIFIAFS NPYNIGDRIR LDGGEAMYIK KIKTYTTEFE
1250
1251
TTTGKIVIYE NSKLSNVKIY NESRSKNAYI DISFKVDINT PLVALKELRK
1300
1301
SLQCLVDSRP SDFCKTKNLY FGYSLQPGHF YEISFWIKCV EGWGNWRKVF
1350
1351
ELRTDIYDFI ILQLRILSIS YRLPTQKIGF TAPLNIADGY NNNNNNNNNN
1400
1401
NNNIQSNYNI NRNINNNMNI NTQQPKINYP PHGNNNFPTH HLRYNRNKPL
1450
1451
QYTSPPKEAR NPLFLETAKH KREFDISSIQ SNNEQHEAPN HIIYNEPVNF
1500
1501
EDQPLKKNKL RSVYNSYKYV ESTNHNNMDT SIENGNGYMY ESYLQKNEDN
1550
1551
NDYFVYNKKK KKNNKKKKTH DFNTKKNINI NNNNNNNNKM NNNKNNLFMN
1600
1601
TFQNNVQSIS SMNNYHDVYY NNDKYYKTLH GQQNLYNNNN IKNINNHENI
1650
1651
DNHNYNKINN ILYNYTNTNL ITSDNSYSYD NKKIIKCNYV PDVSNSDDSN
1700
1701
HTDNMKGNNI YRNNNNFNNN SNNMKVKRGD HFNPIYPYND DIYTAHKNKE
1750
1751
PQNIFENLYK LKKISNTNLD EKNYFSYDSS SGYDSYDCVK HFTYLHDKKQ
1800
1801
NILLKRRKIK MA                                         
1812
 

Show the unformatted sequence.

Checksums:
CRC64:045FCBEAE6159371
MD5:e13b83e492c3a497e0922994d4877e7d

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;