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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: KCC1D_HUMAN (Q8IU85)

Summary

This is the summary of UniProt entry KCC1D_HUMAN (Q8IU85).

Description: Calcium/calmodulin-dependent protein kinase type 1D EC=2.7.11.17
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 385 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 10
Pfam Pkinase 23 279
low_complexity n/a 323 342
low_complexity n/a 357 366
disorder n/a 365 385

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8IU85. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MARENGESSS SWKKQAEDIK KIFEFKETLG TGAFSEVVLA EEKATGKLFA
50
51
VKCIPKKALK GKESSIENEI AVLRKIKHEN IVALEDIYES PNHLYLVMQL
100
101
VSGGELFDRI VEKGFYTEKD ASTLIRQVLD AVYYLHRMGI VHRDLKPENL
150
151
LYYSQDEESK IMISDFGLSK MEGKGDVMST ACGTPGYVAP EVLAQKPYSK
200
201
AVDCWSIGVI AYILLCGYPP FYDENDSKLF EQILKAEYEF DSPYWDDISD
250
251
SAKDFIRNLM EKDPNKRYTC EQAARHPWIA GDTALNKNIH ESVSAQIRKN
300
301
FAKSKWRQAF NATAVVRHMR KLHLGSSLDS SNASVSSSLS LASQKDCLAP
350
351
STLCSFISSS SGVSGVGAER RPRPTTVTAV HSGSK                
385
 

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Checksums:
CRC64:717467D019E30FC9
MD5:82c96c351a3b58cbca8fed3796ac306a

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Pkinase 23 - 279 2JC6 A 23 - 279 Jmol OpenAstexViewer
C 23 - 279 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.