Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ZDH17_HUMAN (Q8IUH5)

Summary

This is the summary of UniProt entry ZDH17_HUMAN (Q8IUH5).

Description: Palmitoyltransferase ZDHHC17 {ECO:0000305}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 632 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
disorder n/a 1 15
disorder n/a 23 27
disorder n/a 35 36
disorder n/a 38 41
Pfam Ank_2 61 154
Pfam Ank_2 161 255
transmembrane n/a 305 321
transmembrane n/a 327 345
transmembrane n/a 357 379
low_complexity n/a 373 385
transmembrane n/a 385 403
Pfam DHHC 434 570
transmembrane n/a 485 506
low_complexity n/a 485 490
transmembrane n/a 539 561

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8IUH5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MQREEGFNTK MADGPDEYDT EAGCVPLLHP EEIKPQSHYN HGYGEPLGRK
50
51
THIDDYSTWD IVKATQYGIY ERCRELVEAG YDVRQPDKEN VTLLHWAAIN
100
101
NRIDLVKYYI SKGAIVDQLG GDLNSTPLHW ATRQGHLSMV VQLMKYGADP
150
151
SLIDGEGCSC IHLAAQFGHT SIVAYLIAKG QDVDMMDQNG MTPLMWAAYR
200
201
THSVDPTRLL LTFNVSVNLG DKYHKNTALH WAVLAGNTTV ISLLLEAGAN
250
251
VDAQNIKGES ALDLAKQRKN VWMINHLQEA RQAKGYDNPS FLRKLKADKE
300
301
FRQKVMLGTP FLVIWLVGFI ADLNIDSWLI KGLMYGGVWA TVQFLSKSFF
350
351
DHSMHSALPL GIYLATKFWM YVTWFFWFWN DLNFLFIHLP FLANSVALFY
400
401
NFGKSWKSDP GIIKATEEQK KKTIVELAET GSLDLSIFCS TCLIRKPVRS
450
451
KHCGVCNRCI AKFDHHCPWV GNCVGAGNHR YFMGYLFFLL FMICWMIYGC
500
501
ISYWGLHCET TYTKDGFWTY ITQIATCSPW MFWMFLNSVF HFMWVAVLLM
550
551
CQMYQISCLG ITTNERMNAR RYKHFKVTTT SIESPFNHGC VRNIIDFFEF
600
601
RCCGLFRPVI VDWTRQYTIE YDQISGSGYQ LV                   
632
 

Show the unformatted sequence.

Checksums:
CRC64:3FD5FD592F2C617F
MD5:bcb9be9d1dc4274f62d2bd35c3d817aa

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Ank_2 161 - 255 3EU9 A 161 - 255 Jmol OpenAstexViewer
B 161 - 255 Jmol OpenAstexViewer
C 161 - 255 Jmol OpenAstexViewer
5W7I A 161 - 255 Jmol OpenAstexViewer
C 161 - 255 Jmol OpenAstexViewer
5W7J A 161 - 255 Jmol OpenAstexViewer
C 161 - 255 Jmol OpenAstexViewer
61 - 154 3EU9 A 61 - 154 Jmol OpenAstexViewer
B 61 - 154 Jmol OpenAstexViewer
C 61 - 154 Jmol OpenAstexViewer
5W7I A 61 - 154 Jmol OpenAstexViewer
C 61 - 154 Jmol OpenAstexViewer
5W7J A 61 - 154 Jmol OpenAstexViewer
C 61 - 154 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.