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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DHX40_HUMAN (Q8IX18)

Summary

This is the summary of UniProt entry DHX40_HUMAN (Q8IX18).

Description: Probable ATP-dependent RNA helicase DHX40 EC=3.6.4.13
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 779 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 29
disorder n/a 40 41
disorder n/a 43 59
Pfam DEAD 53 221
Pfam Helicase_C 253 401
Pfam HA2 463 579
Pfam OB_NTP_bind 619 699
disorder n/a 652 653
low_complexity n/a 709 721
disorder n/a 718 724
disorder n/a 726 728
disorder n/a 734 741
disorder n/a 743 748
disorder n/a 752 779

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8IX18. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSRFPAVAGR APRRQEEGER SRDLQEERLS AVCIADREEK GCTSQEGGTT
50
51
PTFPIQKQRK KIIQAVRDNS FLIVTGNTGS GKTTQLPKYL YEAGFSQHGM
100
101
IGVTQPRKVA AISVAQRVAE EMKCTLGSKV GYQVRFDDCS SKETAIKYMT
150
151
DGCLLKHILG DPNLTKFSVI ILDEAHERTL TTDILFGLLK KLFQEKSPNR
200
201
KEHLKVVVMS ATMELAKLSA FFGNCPIFDI PGRLYPVREK FCNLIGPRDR
250
251
ENTAYIQAIV KVTMDIHLNE MAGDILVFLT GQFEIEKSCE LLFQMAESVD
300
301
YDYDVQDTTL DGLLILPCYG SMTTDQQRRI FLPPPPGIRK CVISTNISAT
350
351
SLTIDGIRYV VDGGFVKQLN HNPRLGLDIL EVVPISKSEA LQRSGRAGRT
400
401
SSGKCFRIYS KDFWNQCMPD HVIPEIKRTS LTSVVLTLKC LAIHDVIRFP
450
451
YLDPPNERLI LEALKQLYQC DAIDRSGHVT RLGLSMVEFP LPPHLTCAVI
500
501
KAASLDCEDL LLPIAAMLSV ENVFIRPVDP EYQKEAEQRH RELAAKAGGF
550
551
NDFATLAVIF EQCKSSGAPA SWCQKHWIHW RCLFSAFRVE AQLRELIRKL
600
601
KQQSDFPKET FEGPKHEVLR RCLCAGYFKN VARRSVGRTF CTMDGRGSPV
650
651
HIHPSSALHE QETKLEWIIF HEVLVTTKVY ARIVCPIRYE WVRDLLPKLH
700
701
EFNAHDLSSV ARREVREDAR RRWTNKENVK QLKDGISKDV LKKMQRRNDD
750
751
KSISDARARF LERKQQRTQD HSDTRKETG                       
779
 

Show the unformatted sequence.

Checksums:
CRC64:B49A996C51986827
MD5:c1022ea2e9080fc90eafc281a72afcb5

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.