Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SP8_HUMAN (Q8IXZ3)

Summary

This is the summary of UniProt entry SP8_HUMAN (Q8IXZ3).

Description: Transcription factor Sp8
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 490 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
low_complexity n/a 10 24
disorder n/a 17 18
low_complexity n/a 35 52
low_complexity n/a 45 59
low_complexity n/a 67 80
low_complexity n/a 94 118
low_complexity n/a 133 148
disorder n/a 136 163
low_complexity n/a 196 208
disorder n/a 228 243
low_complexity n/a 255 275
disorder n/a 283 287
disorder n/a 294 295
low_complexity n/a 296 313
disorder n/a 298 322
disorder n/a 345 346
Pfam zf-C2H2 356 380
Pfam zf-C2H2 386 410
disorder n/a 403 406
disorder n/a 408 409
Pfam zf-C2H2_4 416 439
disorder n/a 431 490
low_complexity n/a 438 457

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8IXZ3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLAATCNKIG SPSPSPSSLS DSSSSFGKGF HPWKRSSSSS SASCNVVGSS
50
51
LSSFGVSGAS RNGGSSSAAA AAAAAAAAAA ALVSDSFSCG GSPGSSAFSL
100
101
TSSSAAAAAA AAAAAASSSP FANDYSVFQA PGVSGGSGGG GGGGGGGSSA
150
151
HSQDGSHQPV FISKVHTSVD GLQGIYPRVG MAHPYESWFK PSHPGLGAAG
200
201
EVGSAGASSW WDVGAGWIDV QNPNSAAALP GSLHPAAGGL QTSLHSPLGG
250
251
YNSDYSGLSH SAFSSGASSH LLSPAGQHLM DGFKPVLPGS YPDSAPSPLA
300
301
GAGGSMLSAG PSAPLGGSPR SSARRYSGRA TCDCPNCQEA ERLGPAGASL
350
351
RRKGLHSCHI PGCGKVYGKT SHLKAHLRWH TGERPFVCNW LFCGKRFTRS
400
401
DELQRHLRTH TGEKRFACPV CNKRFMRSDH LSKHVKTHSG GGGGGGSAGS
450
451
GSGGKKGSDT DSEHSAAGSP PCHSPELLQP PEPGHRNGLE           
490
 

Show the unformatted sequence.

Checksums:
CRC64:8FB659057C6F8E58
MD5:5b8c8111e7649f813c235f32d7facabc

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.