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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CFA46_HUMAN (Q8IYW2)

Summary

This is the summary of UniProt entry CFA46_HUMAN (Q8IYW2).

Description: Cilia- and flagella-associated protein 46 {ECO:0000305}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 2715 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 439 443
disorder n/a 490 498
disorder n/a 564 566
low_complexity n/a 609 625
disorder n/a 626 629
disorder n/a 679 680
disorder n/a 686 692
disorder n/a 846 852
disorder n/a 875 886
disorder n/a 1255 1275
disorder n/a 1345 1347
disorder n/a 1352 1412
low_complexity n/a 1361 1392
coiled_coil n/a 1362 1391
low_complexity n/a 1383 1402
disorder n/a 1438 1448
low_complexity n/a 1543 1557
disorder n/a 1554 1556
low_complexity n/a 1635 1653
coiled_coil n/a 1648 1668
coiled_coil n/a 1783 1810
low_complexity n/a 1951 1966
disorder n/a 2000 2022
low_complexity n/a 2100 2122
disorder n/a 2249 2253
disorder n/a 2255 2257
low_complexity n/a 2268 2285
disorder n/a 2294 2319
low_complexity n/a 2368 2379
disorder n/a 2371 2396
disorder n/a 2535 2536
disorder n/a 2541 2572
low_complexity n/a 2598 2617
disorder n/a 2610 2611
disorder n/a 2613 2615
low_complexity n/a 2614 2627
disorder n/a 2618 2624
low_complexity n/a 2631 2647
disorder n/a 2647 2657

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8IYW2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDLVITQELA RAESQQDAAS LKKAYELIKS ANLGKSEFDP SESFSPDLFV
50
51
LCAEQALKMR QPEVSEDCIQ MYFKVKAPIT QFLGRAHLCR AQMCAPKSAE
100
101
NLEEFENCVT EYMKAINFAK GEPRYYFLVY NASVLYWQMV RPFLKPGYRH
150
151
HLIPSLSQII NVLSQTEEED KEWRAELMLE LLECYLQAGR KEEAARFCST
200
201
AAPFIKSHVP QKYRQIFSVM VRHELMDELQ LKEEKKNSIS LSVTFYINML
250
251
KAKAEQNDLP GDISVILRKA YRHLGHYNHQ RFPSISEEKM LLLFELARFS
300
301
LTLKCMEISS ACLSDLKKME SKDPGKLIEM ECLECESEAL RLESKMKVYN
350
351
RAAVEAQLDI IQRLDVALQR AVRLGDPRVI HVVCATQWNT CLPLLQHNLR
400
401
HHLRKPLAGV ADVLEKLDSL MTLLRCQVHM EMAQIEEDED RLEPATEHLR
450
451
KAARLDSLGL YRDRIQMAST RLRLCTTLYQ APERAEDKAI MAVEQAKKAT
500
501
PKDSVRKKRA LLVNAGLALA PDAFQIVLDS ENEAKVSTGK NRGRFTYLCA
550
551
KAWHHTVSVD KAAGHLRRLG NENDKERIQI WAELAKVARK QGVWDVCRTA
600
601
SRFCLLYDNV KVKKLRLRRG KKKRGRDGSV QDTWSQPEVV LQRQVCPDLL
650
651
RKFAEVGFIH AEATVHLLRS EGVELNDRAI PPEDLSQHPA GYVPEPPEVN
700
701
AEWITYRTWI ESLSRCAMNN WLRSAEIGQE IQEAWIVQNA VVYVLNHNHH
750
751
LILAGRQKEL VDALYHLLSI VKATGHSGDP VMLVTLCNTL ARGLIISWIP
800
801
VQAAEKSRKF MRPNAFHSPL DAGATSEIKT AVEVCEFALN LTNGSAPEET
850
851
VPTGTRQQLI ATWVKAKQLL QQQIGPRLGT EEQGTNEDVS SVTRVLVALE
900
901
MYSCNGLGLM DFTVPSLAQL VKMASECNWS DPLVELQTLT RLTHFAHAAR
950
951
DHETTMACAH RALEMGIKYL KKFGPEESRL VAEMLCTATA IQGRSIMENL
1000
1001
KGRKQLRLVA AKAFTESARF GGIAGSSALV MLAARHYWNA WLPLLSSAVY
1050
1051
RKKAKGALKR LIGIINKTEA RKQEKGKTLL LHQWPTADFQ GGGTTEGYFL
1100
1101
PGAEDDLALR AALYGLLFHS HADQDDWEGG LKVLDEAVQV LPRTAHRLLI
1150
1151
FKHMVIVKAK LGQNFSMEIQ KFKAESEDYL ARMWHRLALN SPSVSGELAC
1200
1201
YNNAIQALQK PEMEWQKVEY LMEFGQWLHH RHFPLEDVVF HLRWAVEILL
1250
1251
AMKPPGDVPE PQPTPDGEYV AVEMPPRSPV SEAEEAVSLE QLRSVRQLEA
1300
1301
LARVHILLAL VLSPGAEGYE DCCLAAYAFF RHIWQVSLMT AGKSVLENRP
1350
1351
LAATSSHLLL PKKEKENERS KEKEKERSKE KENERSKEKD KEKGKEEKVK
1400
1401
EPKQSQSPAP IKQLEDLPMS IEEWASYSCP EEVLSVLKQD RSDSTVNPSS
1450
1451
IQKPTYSLYF LDHLVKALQK MCLHELTVPV LQLGVLISDS VVGSKGLSDL
1500
1501
YHLRLAHACS ELKLREAAAR HEEAVGQVCV SELEQASCRK EIALKKEKNK
1550
1551
EPLLEESLPA LNEQTLPVQP GEIKPLDAKD KILKMNGETG RDLDGTSFPH
1600
1601
LWMLKAEVLL EMNLYQPARL LLSEAYLAFQ ELDEPCAEAQ CLLLLAQLAN
1650
1651
KEKNYGQAKK MIAQAQHLGG SEEFWYNSTL TLAEALLSME HSGREATVCH
1700
1701
IFQKLINAFK ILKKERPNRL PLLEFMITDL EARCLSLRVR VAQHSAVTEP
1750
1751
TECSLLLKEM DDGLLEIERK FIDCGCKENC VDVKLERAKI KRLRAQNEKD
1800
1801
EEQKTAYYLE AYGLAQGAVA EEEGRLHSIQ GLYGLAQGAM AEEEGRLHSV
1850
1851
QGLLSLQDLQ NVNTPLMRKL ARLKLGLVEM ALDMLQFIWE EAHGQQSEQG
1900
1901
SLEKLLADYL QNTSDYTSVG LQWFTLKRTL AHGALAQLGS LQPLSVGCVE
1950
1951
IRARLLGLAG RALHLLAMQA DPVHPTCYWE AGPSVGAKLS GLKSLELEVE
2000
2001
EEGATKSSRD PPASRAAPEE HCRRGEDLKR RMVLAQQYLA QASEVLLQCL
2050
2051
QVALGSGLLD VAAAASLEMV ECVGTLDPAT TCQFLALSQS CSASETMRDV
2100
2101
LLAATANTSS SQLAALLQLQ HQLRCQDRTT TSLGARVEQR LAAVSKAWQN
2150
2151
LCVTEQHFNL LNEMPPTFWI LFLHLSGDRS RLYGAAYEKP KFITAAKGKV
2200
2201
QAVGGSCKVM RLAISPTAFS HLLACAQQFR KQTQAQVYSE DMALNIGSEP
2250
2251
EGLQVEEKER PVQRLSSVLG PLEELLQPLF PLLSLSKARV QTPAVVADSG
2300
2301
KSKGKDKERK TSTGQHSTVQ PEVADKIVLV ADRHLLELPL EGLSVFDEGT
2350
2351
ISSVSREFSL QMLWNRLHKE ETEGGVKKEG RSRDPKKRSL AKKGRKGSIP
2400
2401
RTIPPDCIIV DSDNFKFVVD PYEEAQGPEM LTPVSITQDI LERFQDTFTS
2450
2451
RWAGHLGSKH FPSQAQWEQA LGSCSGFFFY GMESFLSHIL VERLVAMNLQ
2500
2501
ECQVAVLLDL ARSYQSLKRH MESVEHRRSV GRWEANWRNS ASPSEDEWRR
2550
2551
GGEPRRGFSD LEGQAAAAPK LRAPSHHAQL GPVWAAAPSH RVVQAWTCLP
2600
2601
SAAGAPALAS ALGSAPLPTH PHLPAPIPSS QLALPFLGLS PALGAASARD
2650
2651
PPPATSRKAA AWTSSSACLC APWGLRRGWS CVSSRGQDKG GLPLAALVLS
2700
2701
CLDQKTIQTV SLFLI                                      
2715
 

Show the unformatted sequence.

Checksums:
CRC64:693A814CD7068AEC
MD5:268f1efce611be530a6985882ac39580