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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ABCA5_MOUSE (Q8K448)

Summary

This is the summary of UniProt entry ABCA5_MOUSE (Q8K448).

Description: ATP-binding cassette sub-family A member 5
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
View Pfam proteome data.
Length: 1642 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam ABC2_membrane_3 29 416
low_complexity n/a 35 47
transmembrane n/a 36 53
transmembrane n/a 73 92
transmembrane n/a 221 242
low_complexity n/a 242 252
transmembrane n/a 262 285
transmembrane n/a 297 321
low_complexity n/a 326 346
transmembrane n/a 327 348
transmembrane n/a 355 376
transmembrane n/a 396 417
Pfam ABC_tran 497 643
low_complexity n/a 732 743
disorder n/a 810 813
transmembrane n/a 864 882
low_complexity n/a 865 869
transmembrane n/a 966 987
transmembrane n/a 1021 1040
transmembrane n/a 1064 1090
transmembrane n/a 1102 1124
transmembrane n/a 1136 1158
transmembrane n/a 1165 1187
transmembrane n/a 1207 1225
disorder n/a 1254 1263
low_complexity n/a 1261 1266
Pfam ABC_tran 1316 1461
disorder n/a 1343 1344
disorder n/a 1456 1460

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8K448. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MATAIRDVGV WRQTRTLLLK NYLIKCRTKK SSVQEILFPL FFLFWLILVS
50
51
MMHPNKKYEE VSDIELSPMD KFSLSNVILG YTPVTNITSS IMQRVSTDHL
100
101
PKVIVTEEYA NEKELVAASL SKSSNFVGVV FKDTMSYELR FFPEMIPVSS
150
151
IYMNSREGCS KTCDAAQYWS LGFTVLQASI DAAIIQLKTN VSVWSELEST
200
201
KAVIMGEAAV VEIDTFPRGV ILIYLVIAFS PFGYFLAIHI VAEKEKKLKE
250
251
FLKIMGLHDT AFWLSWVLLY ASLIFLMSLL MAVIATASSL FPQSSSIVIF
300
301
LLFFLYGLSS VFFALMLTPL FKKSKHVGVV EFFVTVVFGF VGLLIVLIES
350
351
FPRSLVWLFS PLCQCAFLIG IAQVMHLEDF NEGALFSNLT EGPYPLIITI
400
401
IMLALDSVFY VLLAVYLDQV IPGEFGLRRS SLYFLKPSYW SKNKRNYKEL
450
451
SEGNINGNIS LNEIVEPVSS EFIGKEAIRI SGIQKSYRKK TENVEALRNL
500
501
SFDIYEGQIT ALLGHSGTGK STLMNILCGL CPPSDGFASI YGHRVSEIDE
550
551
MFEARKMIGI CPQSDINFDV LTVEENLSIL ASIKGIPANN IIQEVQKVLL
600
601
DLDMQAIKDN QAKKLSGGQK RKLSVGIAVL GNPKILLLDE PTAGMDPCSR
650
651
HIVWNLLKYR KANRVTVFST HFMDEADILA DRKAVISQGM LKCVGSSIFL
700
701
KSKWGIGYRL SMYIDRYCAT ESLSSLVRQH IPAAALLQQN DQQLVYSLPF
750
751
KDMDKFSGLF SALDIHSNLG VISYGVSMTT LEDVFLKLEV EAEIDQADYS
800
801
VFTQQPREEE TDSKSFDEME QSLLILSETK ASSVSTMSLW KQQVSTIAKF
850
851
HFLSLKRESK SVRAVLLLLL IFFAVQIFMF FLHHSFKNAV VPIKLVPDLY
900
901
FLKPGDKPHK YKTSLLLQNS TDSDINGLIE FFAHQNIMVA MFNDSDYVSA
950
951
APHSAALNVV RSEKDYVFSA VFNSTMVYCL PVMMNIISNY YLYHLNVTEA
1000
1001
IQTWSTPFIQ EITDIVFKIE LYFQAALLGI IVTAMPPYFA MENAENHKIK
1050
1051
AYTQLKLSGL LPSAYWVGQA VVDIPLFFVV LILMLGSLFA FHHGLYFYPA
1100
1101
KFLAVVFCLI AYVPSVILFT YIASFTFKKI LNTKEFWSFI YSVTALACVA
1150
1151
ITETTFFLQY AVTAVFHYTF CIAIPIYPLL GCLISFIKGS WKNMPKNENT
1200
1201
YNPWDRLLVA VIMPYLQCIL WIFLLQHYEK IHGGRSIRKD PFFRALSQKA
1250
1251
KNKKFPEPPI NEDEDEDVKA ERLKVKELMG CQCCEEKPAI MVCNLHKEYD
1300
1301
DKKDFLHSRK TTKVATKYIS FCVKKGEILG LLGPNGAGKS TVINTLVGDV
1350
1351
EPTSGKIFLG DYGSHSSEDD ESIKCMGYCP QTNPLWPDLT LQEHFEIYGA
1400
1401
VKGMSPGDMK EVISRITKAL DLKEHLQKTV KKLPAGIKRK LCFALSMLGN
1450
1451
PQVTLLDEPS TGMDPRAKQH MWRAIRTAFK NKKRAALLTT HYMEEAEAVC
1500
1501
DRVAIMVSGQ LRCIGTVQHL KSKFGKGYFL EIKLKDWIEN LEIDRLQREI
1550
1551
QYIFPNASRQ ESFSSILAFK IPKEDVQSLS QSFAKLEEAK RTFAIEEYSF
1600
1601
SQATLEQVFV ELTKEQEEED NSCGTLASTL WWERTQEDRV VF        
1642
 

Show the unformatted sequence.

Checksums:
CRC64:177A5FC0B075DFC5
MD5:46a89c1bde20ac50f6fbc1cecfcb724b

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.