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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: FTMT_HUMAN (Q8N4E7)

Summary

This is the summary of UniProt entry FTMT_HUMAN (Q8N4E7).

Description: Ferritin, mitochondrial EC=1.16.3.1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 242 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 17
low_complexity n/a 39 57
disorder n/a 43 72
Pfam Ferritin 77 218
disorder n/a 125 133
disorder n/a 140 145
disorder n/a 239 242

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8N4E7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLSCFRLLSR HISPSLASLR PVRCCFALPL RWAPGRPLDP RQIAPRRPLA
50
51
AAASSRDPTG PAAGPSRVRQ NFHPDSEAAI NRQINLELYA SYVYLSMAYY
100
101
FSRDDVALNN FSRYFLHQSR EETEHAEKLM RLQNQRGGRI RLQDIKKPEQ
150
151
DDWESGLHAM ECALLLEKNV NQSLLELHAL ASDKGDPHLC DFLETYYLNE
200
201
QVKSIKELGD HVHNLVKMGA PDAGLAEYLF DTHTLGNENK QN        
242
 

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Checksums:
CRC64:29E4B41616A74A3F
MD5:5bf9a976211b63c17c5b4b622a2e53a8

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Ferritin 77 - 218 1R03 A 17 - 158 Jmol OpenAstexViewer
5Z8J A 17 - 158 Jmol OpenAstexViewer
5Z8S A 17 - 158 Jmol OpenAstexViewer
5Z8U A 17 - 158 Jmol OpenAstexViewer
B 17 - 158 Jmol OpenAstexViewer
5Z91 A 17 - 158 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.