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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: ZGPAT_HUMAN (Q8N5A5)

Summary

This is the summary of UniProt entry ZGPAT_HUMAN (Q8N5A5).

Description: Zinc finger CCCH-type with G patch domain-containing protein
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 531 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 5
coiled_coil n/a 3 23
disorder n/a 7 8
disorder n/a 24 42
disorder n/a 64 85
low_complexity n/a 83 95
disorder n/a 90 133
low_complexity n/a 106 127
disorder n/a 150 151
disorder n/a 153 154
Pfam zf-CCCH_4 178 199
disorder n/a 266 291
low_complexity n/a 275 286
Pfam G-patch 333 376
disorder n/a 359 365
disorder n/a 378 419
low_complexity n/a 394 411
low_complexity n/a 421 437
disorder n/a 426 448
disorder n/a 450 453
coiled_coil n/a 452 479
disorder n/a 458 461
disorder n/a 466 468
disorder n/a 470 531
coiled_coil n/a 491 518

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8N5A5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDEESLESAL QTYRAQLQQV ELALGAGLDS SEQADLRQLQ GDLKELIELT
50
51
EASLVSVRKS SLLAALDEER PGRQEDAEYQ AFREAITEAV EAPAAARGSG
100
101
SETVPKAEAG PESAAGGQEE EEGEDEEELS GTKVSAPYYS SWGTLEYHNA
150
151
MVVGTEEAED GSAGVRVLYL YPTHKSLKPC PFFLEGKCRF KENCRFSHGQ
200
201
VVSLDELRPF QDPDLSSLQA GSACLAKHQD GLWHAARITD VDNGYYTVKF
250
251
DSLLLREAVV EGDGILPPLR TEATESDSDS DGTGDSSYAR VVGSDAVDSA
300
301
QSSALCPSLA VVGSDAVDSG TCSSAFAGWE VHTRGIGSRL LTKMGYEFGK
350
351
GLGRHAEGRV EPIHAVVLPR GKSLDQCVET LQKQTRVGKA GTNKPPRCRG
400
401
RGARPGGRPA PRNVFDFLNE KLQGQAPGAL EAGAAPAGRR SKDMYHASKS
450
451
AKRALSLRLF QTEEKIERTQ RDIRSIQEAL ARNAGRHSVA SAQLQEKLAG
500
501
AQRQLGQLRA QEAGLQQEQR KADTHKKMTE F                    
531
 

Show the unformatted sequence.

Checksums:
CRC64:36572156BABDA876
MD5:2896af0a39b492e27d31778b514bfb8c

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
zf-CCCH_4 178 - 199 4II1 A 178 - 199 Jmol OpenAstexViewer
B 178 - 199 Jmol OpenAstexViewer
C 178 - 199 Jmol OpenAstexViewer
D 178 - 199 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.