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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: GBP7_HUMAN (Q8N8V2)

Summary

This is the summary of UniProt entry GBP7_HUMAN (Q8N8V2).

Description: Guanylate-binding protein 7
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 638 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam GBP 18 281
transmembrane n/a 30 47
transmembrane n/a 114 131
Pfam GBP_C 283 579
coiled_coil n/a 384 404
coiled_coil n/a 481 551
low_complexity n/a 484 502
disorder n/a 491 493
low_complexity n/a 497 520
disorder n/a 499 521
disorder n/a 527 529
disorder n/a 541 543
coiled_coil n/a 561 588
disorder n/a 579 581

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8N8V2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MASEIHMPGP VCLTENTKGH LVVNSEALEI LSAITQPVVV VAIVGLYRTG
50
51
KSYLMNKLAG KNKGFPLGCT VKSETKGIWM WCVPHPSKPN HTLILLDTEG
100
101
LGDMEKSDPK SDSWIFALAV LLSSSFVYNS MGTINHQALE QLHYVTELTE
150
151
LIRAKSCPRP DEVEDSSEFV SFFPDFIWTV RDFTLELKLD GHPITEDEYL
200
201
ENALKLISGK NPQIQNSNKP REWIRHFFPK QKCFVFDRPI NDKKLLLHVE
250
251
EVREDQLDSN FQMQSENFCS YIFTHAKTKT LREGILVTGN RLGMLVETYL
300
301
DAINSGATPC LENAMAVLAQ CENSAAVQRA ANHYSQQMAQ QVRFPTDTLQ
350
351
ELLDVHAVCE REAIAVFMEY SFKDKSQEFQ KKLVDTMEKK KEDFVLQNEE
400
401
ASAKYCQAEL KRLSELLTES ISRGTFFVPG GHNIYLEAKK KIEQDYTLVP
450
451
RKGVKADEVL QSFLQSQVVI EESILQSDKA LTAGEKAIAA KQAKKEAAEK
500
501
EQELLRQKQK EQQQMMEAQE RSFQENIAQL KKKMEREREN YMRELRKMLS
550
551
HKMKVLEELL TEGFKEIFES LNEEINRLKE QIEAAENEEP SVFSQILDVA
600
601
GSIFIAALPG AAKLVDLGMK ILSSLCNRLR NPGKKIIS             
638
 

Show the unformatted sequence.

Checksums:
CRC64:A9F86253BED61276
MD5:de6c41f38b9abe469fce389550825b83

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.