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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: FSIP1_HUMAN (Q8NA03)

Summary

This is the summary of UniProt entry FSIP1_HUMAN (Q8NA03).

Description: Fibrous sheath-interacting protein 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 581 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam FSIP1 2 394
disorder n/a 3 87
disorder n/a 93 99
disorder n/a 102 107
coiled_coil n/a 108 142
disorder n/a 109 116
low_complexity n/a 121 132
disorder n/a 126 127
low_complexity n/a 131 142
disorder n/a 162 163
disorder n/a 177 184
disorder n/a 186 204
disorder n/a 207 208
disorder n/a 210 212
disorder n/a 215 216
disorder n/a 231 234
disorder n/a 241 243
disorder n/a 257 258
disorder n/a 266 268
low_complexity n/a 273 299
disorder n/a 287 300
disorder n/a 336 377
coiled_coil n/a 375 395
disorder n/a 379 385
disorder n/a 389 390
disorder n/a 462 471
disorder n/a 556 581

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8NA03. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDIIKGNLDG ISKPASNSRI RPGSRSSNAS LEVLSTEPGS FKVDTASNLN
50
51
SGKEDHSESS NTENRRTSND DKQESCSEKI KLAEEGSDED LDLVQHQIIS
100
101
ECSDEPKLKE LDSQLQDAIQ KMKKLDKILA KKQRREKEIK KQGLEMRIKL
150
151
WEEIKSAKYS EAWQSKEEME NTKKFLSLTA VSEETVGPSH EEEDTFSSVF
200
201
HTQIPPEEYE MQMQKLNKDF TCDVERNESL IKSGKKPFSN TEKIELRGKH
250
251
NQDFIKRNIE LAKESRNPVV MVDREKKRLV ELLKDLDEKD SGLSSSEGDQ
300
301
SGWVVPVKGY ELAVTQHQQL AEIDIKLQEL SAASPTISSF SPRLENRNNQ
350
351
KPDRDGERNM EVTPGEKILR NTKEQRDLHN RLREIDEKLK MMKENVLEST
400
401
SCLSEEQLKC LLDECILKQK SIIKLSSERK KEDIEDVTPV FPQLSRSIIS
450
451
KLLNESETKV QKTEVEDADM LESEECEASK GYYLTKALTG HNMSEALVTE
500
501
AENMKCLQFS KDVIISDTKD YFMSKTLGIG RLKRPSFLDD PLYGISVSLS
550
551
SEDQHLKLSS PENTIADEQE TKDAAEECKE P                    
581
 

Show the unformatted sequence.

Checksums:
CRC64:979A8B4DE2177C74
MD5:96f03f4556d4d629992f4f5f1833bfb3

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;