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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TTC13_HUMAN (Q8NBP0)

Summary

This is the summary of UniProt entry TTC13_HUMAN (Q8NBP0).

Description: Tetratricopeptide repeat protein 13
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 860 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 19
low_complexity n/a 4 40
disorder n/a 60 61
disorder n/a 65 74
disorder n/a 133 136
Pfam TPR_8 216 248
Pfam TPR_16 254 314
Pfam TPR_1 317 350

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8NBP0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAPAGCCCCC CFWGGAVAAA GAARRVLLLL LLGVLSAGLR PGALATEHYS
50
51
PLSLLKQELQ HRQQQEAPAG GGGCSPQSGD WGDQYSAECG ESSFLNFHDS
100
101
DCEPKGSSPC DSLLSLNTEK ILSQAKSIAE QKRFPFATDN DSTNEELAIA
150
151
YVLIGSGLYD EAIRHFSTML QEEPDLVSAI YGRGIAYGKK GLHDIKNAEL
200
201
ALFELSRVIT LEPDRPEVFE QRAEILSPLG RINEAVNDLT KAIQLQPSAR
250
251
LYRHRGTLYF ISEDYATAHE DFQQSLELNK NQPIAMLYKG LTFFHRGLLK
300
301
EAIESFKEAL KQKVDFIDAY KSLGQAYREL GNFEAATESF QKALLLNQNH
350
351
VQTLQLRGMM LYHHGSLQEA LKNFKRCLQL EPYNEVCQYM KGLSHVAMGQ
400
401
FYEGIKAQTK VMLNDPLPGQ KASPEYLKVK YLREYSRYLH AHLDTPLTEY
450
451
NIDVDLPGSF KDHWAKNLPF LIEDYEEQPG LQPHIKDVLH QNFESYKPEV
500
501
QELICVADRL GSLMQYETPG FLPNKRIHRA MGLAALEVMQ AVQRTWTNSK
550
551
VRMNGKTRLM QWRDMFDIAV KWRRIADPDQ PVLWLDQMPA RSLSRGFNNH
600
601
INLIRGQVIN MRYLEYFEKI LHFIKDRILV YHGANNPKGL LEVREALEKV
650
651
HKVEDLLPIM KQFNTKTKDG FTVNTKVPSL KDQGKEYDGF TITITGDKVG
700
701
NILFSVETQT TEERTQLYHA EIDALYKDLT AKGKVLILSS EFGEADAVCN
750
751
LILSLVYYFY NLMPLSRGSS VIAYSVIVGA LMASGKEVAG KIPKGKLVDF
800
801
EAMTAPGSEA FSKVAKSWMN LKSISPSYKT LPSVSETFPT LRSMIEVLNT
850
851
DSSPRCLKKL                                            
860
 

Show the unformatted sequence.

Checksums:
CRC64:75747278086D7160
MD5:f1f13f5d09c1fae62847638e53a5a8c3

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;