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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SMG8_HUMAN (Q8ND04)

Summary

This is the summary of UniProt entry SMG8_HUMAN (Q8ND04).

Description: Protein SMG8
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 991 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 13 14
disorder n/a 16 41
low_complexity n/a 18 40
Pfam Smg8_Smg9 41 985
disorder n/a 79 80
disorder n/a 82 125
low_complexity n/a 94 113
low_complexity n/a 108 122
disorder n/a 279 299
disorder n/a 378 380
disorder n/a 392 393
low_complexity n/a 395 401
disorder n/a 432 436
disorder n/a 582 601
disorder n/a 610 614
disorder n/a 652 697
disorder n/a 702 735
disorder n/a 737 743
disorder n/a 747 748
disorder n/a 809 820
disorder n/a 828 831
low_complexity n/a 833 844
low_complexity n/a 924 938
disorder n/a 938 939

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8ND04. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAGPVSLRDL LMGASAWMGS ESPGGSPTEG GGSAAGGPEP PWREDEICVV
50
51
GIFGKTALRL NSEKFSLVNT VCDRQVFPLF RHQDPGDPGP GIRTEAGAVG
100
101
EAGGAEDPGA AAGGSVRGSG AVAEGNRTEA GSQDYSLLQA YYSQESKVLY
150
151
LLLTSICDNS QLLRACRALQ SGEAGGGLSL PHAEAHEFWK HQEKLQCLSL
200
201
LYLFSVCHIL LLVHPTCSFD ITYDRVFRAL DGLRQKVLPL LKTAIKDCPV
250
251
GKDWKLNCRP CPPRLLFLFQ LNGALKVEPP RNQDPAHPDK PKKHSPKRRL
300
301
QHALEDQIYR IFRKSRVLTN QSINCLFTVP ANQAFVYIVP GSQEEDPVGM
350
351
LLDQLRSHCT VKDPESLLVP APLSGPRRYQ VMRQHSRQQL SFHIDSSSSS
400
401
SSGQLVDFTL REFLWQHVEL VLSKKGFDDS VGRNPQPSHF ELPTYQKWIS
450
451
AASKLYEVAI DGKEEDLGSP TGELTSKILS SIKVLEGFLD IDTKFSENRC
500
501
QKALPMAHSA YQSNLPHNYT MTVHKNQLAQ ALRVYSQHAR GPAFHKYAMQ
550
551
LHEDCYKFWS NGHQLCEERS LTDQHCVHKF HSLPKSGEKP EADRNPPVLY
600
601
HNSRARSTGA CNCGRKQAPR DDPFDIKAAN YDFYQLLEEK CCGKLDHINF
650
651
PVFEPSTPDP APAKNESSPA PPDSDADKLK EKEPQTQGES TSLSLALSLG
700
701
QSTDSLGTYP ADPQAGGDNP EVHGQVEVKT EKRPNFVDRQ ASTVEYLPGM
750
751
LHSNCPKGLL PKFSSWSLVK LGPAKSYNFH TGLDQQGFIP GTNYLMPWDI
800
801
VIRTRAEDEG DLDTNSWPAP NKAIPGKRSA VVMGRGRRRD DIARAFVGFE
850
851
YEDSRGRRFM CSGPDKVMKV MGSGPKESAL KALNSDMPLY ILSSSQGRGL
900
901
KPHYAQLMRL FVVVPDAPLQ IILMPQVQPG PPPCPVFYPE KQEITLPPDG
950
951
LWVLRFPYAY VTERGPCFPP KENVQLMSYK VLRGVLKAVT Q         
991
 

Show the unformatted sequence.

Checksums:
CRC64:9D8168B171179CFF
MD5:2bad8a98d3178e426b4412a08c16bcb3

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.