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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HMGC2_HUMAN (Q8TB92)

Summary

This is the summary of UniProt entry HMGC2_HUMAN (Q8TB92).

Description: 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic EC=4.1.3.4
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 370 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam HMGL-like 77 351
low_complexity n/a 329 340

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8TB92. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGNVPSAVKH CLSYQQLLRE HLWIGDSVAG ALDPAQTSLL TNLHCFQPDV
50
51
SGFSVSLAGT VACIHWETSQ LSGLPEFVKI VEVGPRDGLQ NEKVIVPTDI
100
101
KIEFINRLSQ TGLSVIEVTS FVSSRWVPQM ADHTEVMKGI HQYPGVRYPV
150
151
LTPNLQGFHH AVAAGATEIS VFGAASESFS KKNINCSIEE SMGKFEEVVK
200
201
SARHMNIPAR GYVSCALGCP YEGSITPQKV TEVSKRLYGM GCYEISLGDT
250
251
IGVGTPGSMK RMLESVMKEI PPGALAVHCH DTYGQALANI LTALQMGINV
300
301
VDSAVSGLGG CPYAKGASGN VATEDLIYML NGLGLNTGVN LYKVMEAGDF
350
351
ICKAVNKTTN SKVAQASFNA                                 
370
 

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Checksums:
CRC64:7DDEE81555E092A1
MD5:57f551d7e404aa79afa4ec99fd099841

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.