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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: NANP_HUMAN (Q8TBE9)

Summary

This is the summary of UniProt entry NANP_HUMAN (Q8TBE9).

Description: N-acylneuraminate-9-phosphatase EC=3.1.3.29
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 248 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam HAD_2 9 208

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8TBE9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGLSRVRAVF FDLDNTLIDT AGASRRGMLE VIKLLQSKYH YKEEAEIICD
50
51
KVQVKLSKEC FHPYNTCITD LRTSHWEEAI QETKGGAANR KLAEECYFLW
100
101
KSTRLQHMTL AEDVKAMLTE LRKEVRLLLL TNGDRQTQRE KIEACACQSY
150
151
FDAVVVGGEQ REEKPAPSIF YYCCNLLGVQ PGDCVMVGDT LETDIQGGLN
200
201
AGLKATVWIN KNGIVPLKSS PVPHYMVSSV LELPALLQSI DCKVSMST  
248
 

Show the unformatted sequence.

Checksums:
CRC64:360E6D7AB965294B
MD5:4071363a8748c473eb6ba57c37657587

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
HAD_2 9 - 208 2W4M A 9 - 208 Jmol OpenAstexViewer
4KNV A 9 - 208 Jmol OpenAstexViewer
B 9 - 208 Jmol OpenAstexViewer
4KNW A 11 - 210 Jmol OpenAstexViewer
B 11 - 210 Jmol OpenAstexViewer
C 11 - 210 Jmol OpenAstexViewer

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.