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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RDH11_HUMAN (Q8TC12)

Summary

This is the summary of UniProt entry RDH11_HUMAN (Q8TC12).

Description: Retinol dehydrogenase 11
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 318 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 22
low_complexity n/a 4 17
Pfam adh_short 42 247
low_complexity n/a 150 164

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8TC12. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVELMFPLLL LLLPFLLYMA APQIRKMLSS GVCTSTVQLP GKVVVVTGAN
50
51
TGIGKETAKE LAQRGARVYL ACRDVEKGEL VAKEIQTTTG NQQVLVRKLD
100
101
LSDTKSIRAF AKGFLAEEKH LHVLINNAGV MMCPYSKTAD GFEMHIGVNH
150
151
LGHFLLTHLL LEKLKESAPS RIVNVSSLAH HLGRIHFHNL QGEKFYNAGL
200
201
AYCHSKLANI LFTQELARRL KGSGVTTYSV HPGTVQSELV RHSSFMRWMW
250
251
WLFSFFIKTP QQGAQTSLHC ALTEGLEILS GNHFSDCHVA WVSAQARNET
300
301
IARRLWDVSC DLLGLPID                                   
318
 

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Checksums:
CRC64:5B0C366552774835
MD5:0c40322c1c3dcb60629c2ec05128d8f5

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;