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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RHPN1_HUMAN (Q8TCX5)

Summary

This is the summary of UniProt entry RHPN1_HUMAN (Q8TCX5).

Description: Rhophilin-1 {ECO:0000305}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 670 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 21
disorder n/a 23 24
Pfam HR1 36 97
disorder n/a 41 46
disorder n/a 51 60
low_complexity n/a 81 91
disorder n/a 92 100
disorder n/a 106 108
Pfam BRO1 109 510
disorder n/a 152 153
low_complexity n/a 304 318
disorder n/a 374 402
disorder n/a 462 487
Pfam PDZ 513 590
low_complexity n/a 584 599
low_complexity n/a 599 614
disorder n/a 607 609
disorder n/a 616 626
disorder n/a 632 637
disorder n/a 639 670
low_complexity n/a 649 661

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8TCX5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MILEERPDGA GAGEESPRLQ GCDSLTQIQC GQLQSRRAQI HQQIDKELQM
50
51
RTGAENLYRA TSNNRVRETV ALELSYVNSN LQLLKEELEE LSGGVDPGRH
100
101
GSEAVTVPMI PLGLKETKEL DWSTPLKELI SVHFGEDGAS YEAEIRELEA
150
151
LRQAMRTPSR NESGLELLTA YYNQLCFLDA RFLTPARSLG LFFHWYDSLT
200
201
GVPAQQRALA FEKGSVLFNI GALHTQIGAR QDRSCTEGAR RAMEAFQRAA
250
251
GAFSLLRENF SHAPSPDMSA ASLCALEQLM MAQAQECVFE GLSPPASMAP
300
301
QDCLAQLRLA QEAAQVAAEY RLVHRTMAQP PVHDYVPVSW TALVHVKAEY
350
351
FRSLAHYHVA MALCDGSPAT EGELPTHEQV FLQPPTSSKP RGPVLPQELE
400
401
ERRQLGKAHL KRAILGQEEA LRLHALCRVL REVDLLRAVI SQTLQRSLAK
450
451
YAELDREDDF CEAAEAPDIQ PKTHQKPEAR MPRLSQGKGP DIFHRLGPLS
500
501
VFSAKNRWRL VGPVHLTRGE GGFGLTLRGD SPVLIAAVIP GSQAAAAGLK
550
551
EGDYIVSVNG QPCRWWRHAE VVTELKAAGE AGASLQVVSL LPSSRLPSLG
600
601
DRRPVLLGPR GLLRSQREHG CKTPASTWAS PRPLLNWSRK AQQGKTGGCP
650
651
QPCAPVKPAP PSSLKHPGWP                                 
670
 

Show the unformatted sequence.

Checksums:
CRC64:CE8C01B716465FF0
MD5:70805f9fcf2c0c72edaef5882a24aff2

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;