Summary
This is the summary of UniProt entry LMX1A_HUMAN (Q8TE12).
| Description: | LIM homeobox transcription factor 1-alpha |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
|
| Length: | 382 amino acids |
| Reference Proteome: |
|
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
Download the data used to generate the domain graphic in JSON format.
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| Source | Domain | Start | End |
|---|---|---|---|
| Pfam | LIM | 35 | 90 |
| Pfam | LIM | 94 | 152 |
| disorder | n/a | 173 | 174 |
| disorder | n/a | 176 | 204 |
| Pfam | Homeodomain | 196 | 252 |
| coiled_coil | n/a | 243 | 263 |
| disorder | n/a | 249 | 290 |
| low_complexity | n/a | 255 | 269 |
| disorder | n/a | 293 | 294 |
| disorder | n/a | 310 | 340 |
| low_complexity | n/a | 337 | 350 |
| disorder | n/a | 346 | 353 |
| disorder | n/a | 356 | 357 |
| disorder | n/a | 359 | 360 |
| disorder | n/a | 363 | 367 |
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession Q8TE12. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MLDGLKMEEN FQSAIDTSAS FSSLLGRAVS PKSVCEGCQR VILDRFLLRL
50 51
NDSFWHEQCV QCASCKEPLE TTCFYRDKKL YCKYDYEKLF AVKCGGCFEA
100 101
IAPNEFVMRA QKSVYHLSCF CCCVCERQLQ KGDEFVLKEG QLLCKGDYEK
150 151
ERELLSLVSP AASDSGKSDD EESLCKSAHG AGKGTAEEGK DHKRPKRPRT
200 201
ILTTQQRRAF KASFEVSSKP CRKVRETLAA ETGLSVRVVQ VWFQNQRAKM
250 251
KKLARRQQQQ QQDQQNTQRL SSAQTNGGGS AGMEGIMNPY TALPTPQQLL
300 301
AIEQSVYSSD PFRQGLTPPQ MPGDHMHPYG AEPLFHDLDS DDTSLSNLGD
350 351
CFLATSEAGP LQSRVGNPID HLYSMQNSYF TS
382
Show the unformatted sequence. |
| Checksums: |
CRC64:55424762757FF5FD
MD5:35138423df248bb33b4fb570235d232a
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.
AlphaFold Structure Prediction
The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.
Model confidence scale
| Very High (pLDDT > 90) | |
| Confident (90 > pLDDT > 70) | |
| Low (70 > pLDDT > 50) | |
| Very Low (pLDDT < 50) |
