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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: LRC15_HUMAN (Q8TF66)

Summary

This is the summary of UniProt entry LRC15_HUMAN (Q8TF66).

Description: Leucine-rich repeat-containing protein 15
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 581 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 21
low_complexity n/a 119 140
Pfam LRR_8 149 209
Pfam LRR_8 197 257
Pfam LRR_8 245 305
Pfam LRR_8 293 353
Pfam LRR_8 365 424
low_complexity n/a 394 403
disorder n/a 487 490
disorder n/a 492 498
low_complexity n/a 498 509
disorder n/a 500 504
disorder n/a 506 508
low_complexity n/a 537 551
transmembrane n/a 539 564
low_complexity n/a 548 563

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8TF66. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPLKHYLLLL VGCQAWGAGL AYHGCPSECT CSRASQVECT GARIVAVPTP
50
51
LPWNAMSLQI LNTHITELNE SPFLNISALI ALRIEKNELS RITPGAFRNL
100
101
GSLRYLSLAN NKLQVLPIGL FQGLDSLESL LLSSNQLLQI QPAHFSQCSN
150
151
LKELQLHGNH LEYIPDGAFD HLVGLTKLNL GKNSLTHISP RVFQHLGNLQ
200
201
VLRLYENRLT DIPMGTFDGL VNLQELALQQ NQIGLLSPGL FHNNHNLQRL
250
251
YLSNNHISQL PPSVFMQLPQ LNRLTLFGNS LKELSPGIFG PMPNLRELWL
300
301
YDNHISSLPD NVFSNLRQLQ VLILSRNQIS FISPGAFNGL TELRELSLHT
350
351
NALQDLDGNV FRMLANLQNI SLQNNRLRQL PGNIFANVNG LMAIQLQNNQ
400
401
LENLPLGIFD HLGKLCELRL YDNPWRCDSD ILPLRNWLLL NQPRLGTDTV
450
451
PVCFSPANVR GQSLIIINVN VAVPSVHVPE VPSYPETPWY PDTPSYPDTT
500
501
SVSSTTELTS PVEDYTDLTT IQVTDDRSVW GMTQAQSGLA IAAIVIGIVA
550
551
LACSLAACVG CCCCKKRSQA VLMQMKAPNE C                    
581
 

Show the unformatted sequence.

Checksums:
CRC64:1CA7B1752C7FE5B3
MD5:80fb961ba1ac7d541a676cab9538848c

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.