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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: S22AH_HUMAN (Q8WUG5)

Summary

This is the summary of UniProt entry S22AH_HUMAN (Q8WUG5).

Description: Solute carrier family 22 member 17
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 538 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
low_complexity n/a 33 54
Pfam Sugar_tr 89 507
transmembrane n/a 96 118
transmembrane n/a 130 149
low_complexity n/a 131 156
transmembrane n/a 155 174
low_complexity n/a 156 167
transmembrane n/a 186 209
low_complexity n/a 188 199
low_complexity n/a 192 209
transmembrane n/a 215 237
transmembrane n/a 304 321
transmembrane n/a 341 359
transmembrane n/a 366 386
transmembrane n/a 410 435
low_complexity n/a 444 463
transmembrane n/a 447 467
transmembrane n/a 473 493
low_complexity n/a 479 493
disorder n/a 528 529

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8WUG5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MASDPIFTLA PPLHCHYGAF PPNASGWEQP PNASGVSVAS AALAASAASR
50
51
VATSTDPSCS GFAPPDFNHC LKDWDYNGLP VLTTNAIGQW DLVCDLGWQV
100
101
ILEQILFILG FASGYLFLGY PADRFGRRGI VLLTLGLVGP CGVGGAAAGS
150
151
STGVMALRFL LGFLLAGVDL GVYLMRLELC DPTQRLRVAL AGELVGVGGH
200
201
FLFLGLALVS KDWRFLQRMI TAPCILFLFY GWPGLFLESA RWLIVKRQIE
250
251
EAQSVLRILA ERNRPHGQML GEEAQEALQD LENTCPLPAT SSFSFASLLN
300
301
YRNIWKNLLI LGFTNFIAHA IRHCYQPVGG GGSPSDFYLC SLLASGTAAL
350
351
ACVFLGVTVD RFGRRGILLL SMTLTGIASL VLLGLWDCEH PIFPTVWAQQ
400
401
GNPNRDLNEA AITTFSVLGL FSSQAAAILS TLLAAEVIPT TVRGRGLGLI
450
451
MALGALGGLS GPAQRLHMGH GAFLQHVVLA ACALLCILSI MLLPETKRKL
500
501
LPEVLRDGEL CRRPSLLRQP PPTRCDHVPL LATPNPAL             
538
 

Show the unformatted sequence.

Checksums:
CRC64:B332F4ED80BF2387
MD5:c061eb023ed0c6253806d75a0e721b49

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;